Category- Suppliments
About Alfacalcidol 500 mg + Calcium 0.00025 mg
Alfacalcidol 0.25 mcg + Calcium 500 mg tablet is an oral nutritional supplement. Alfacalcidol 500 mg + Calcium 0.00025 mg tablet is used to treat like calcium deficiency, vitamin D deficiency, osteoporosis, weak bones, fracture healing, kidney-related bone disorders, and in elderly people or postmenopausal women.
Calcium helps in building and maintaining strong bones and teeth. Alfacalcidol is an active form of vitamin D that helps the body absorb calcium more effectively and maintain proper calcium levels in the blood, especially in people with kidney problems.
Common side effects include constipation, diarrhea, stomach upset, abdominal pain, nausea, vomiting, and bloating. Taking it after food helps reduce stomach discomfort. Avoid taking more than prescribed, as excess intake may lead to high calcium levels (hypercalcemia), causing weakness, confusion, or kidney problems.
Medicine Highlights
| Uses | 1. To treat calcium deficiency 2. To prevent and treat osteoporosis (weak and brittle bones) 3. To support bone strength and fracture healing 4. To improve calcium absorption in the body 5. To support healthy teeth and muscle function 6. To manage vitamin D deficiency |
| Common Side Effects | 1. Constipation 2. Diarrhea 3. Stomach upset 4. Abdominal pain 5. Nausea 6. Vomiting 7. Bloating 8. Loss of appetite |
| Additional Information | 1. Take at the same time each day to maintain consistent levels in the body. 2. Do not crush, chew, or break the tablet. |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | This medicine should be taken orally with a sip of water. |
Alfacalcidol 500 mg + Calcium 0.00025 mg Uses
Alfacalcidol 500 mg + Calcium 0.00025 mg is used to treat and relieve symptoms of the following conditions:
- Calcium deficiency (weak bones, muscle cramps, low calcium levels)
- Vitamin D deficiency
- Osteoporosis (weak and brittle bones)
- Bone weakness and fracture healing support
- Muscle weakness due to low calcium or vitamin D
- Support overall bone and teeth health
Alfacalcidol 500 mg + Calcium 0.00025 mg side effects
More Common
- Nausea
- Stomach discomfort
- Constipation
- Loose stools or diarrhea
- Dark/black stools
- Vomiting
- Headache
- Metallic taste in mouth
Less Common
- Bloating
- Loss of appetite
- Skin rash
- Itching
- Dizziness
- Allergic reaction
How Alfacalcidol 500 mg + Calcium 0.00025 mg works
Alfacalcidol 500 mg + Calcium 0.00025 mg tablet works by providing essential nutrients for bone health. Calcium strengthens bones and teeth. Alfacalcidol is converted into an active form of vitamin D in the body, which increases calcium absorption from the intestine, maintains calcium levels in the blood, and reduces calcium loss from the kidneys. Together, they improve bone strength and support muscle function.
Alfacalcidol 500 mg + Calcium 0.00025 mg Interaction with Other Medicines
Avoid taking Alfacalcidol 500 mg + Calcium 0.00025 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Alfacalcidol 500 mg + Calcium 0.00025 mg Interaction with Food Product
Avoid taking it at the same time with tea, coffee, excess fiber, spinach, and high-phytate foods, as they reduce calcium absorption. Take with water after food for better absorption.
Intake routine/cycle
Daily dose
Take Alfacalcidol 500 mg + Calcium 0.00025 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
Missed Dose
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Recommended Dietary Allowance (RDA)
Calcium
The recommended dietary allowance for calcium in adults is about 1000 mg per day. Women above 50 years and older adults may need around 1200 mg per day. Children need around 700–1300 mg depending on age.
Alfacalcidol
There is no fixed recommended dietary allowance for alfacalcidol, as it is an active form of vitamin D. The dose is determined by the doctor based on the individual’s medical condition and needs.
Natural Source of Alfacalcidol 500 mg + Calcium 0.00025 mg Cholecalciferol 500 iu
Calcium
Calcium is found in milk, curd, cheese, yogurt, paneer, leafy green vegetables, almonds, sesame seeds, tofu, and fortified foods.
Alfacalcidol
Vitamin D is found in sunlight exposure, egg yolk, fatty fish, fortified milk, fortified cereals, and mushrooms.
FAQ’s
What are the uses of Alfacalcidol 500 mg + Calcium 0.00025 mg capsules?
Alfacalcidol and Calcium capsules are used to treat calcium deficiency and vitamin D deficiency. They help in preventing and managing osteoporosis, improving bone strength, supporting fracture healing, and maintaining healthy teeth and muscle function. They are also useful in managing bone problems related to kidney disease.
What are the side effects of Alfacalcidol 500 mg + Calcium 0.00025 mg capsules?
Common side effects of Alfacalcidol 500 mg + Calcium 0.00025 mg are constipation, diarrhea, stomach upset, abdominal pain, nausea, vomiting, bloating, and loss of appetite. In some cases, it may increase calcium levels in the blood, leading to weakness or confusion.
What are the contraindications of Alfacalcidol 500 mg + Calcium 0.00025 mg capsules?
These capsules should not be used in patients with high calcium levels in the blood (hypercalcemia), excess vitamin D levels, kidney stones, or allergy to any of its components. It should be used carefully in patients with kidney disease under medical supervision.
Reference
- National Institutes of Health. Calcium [Internet]. National Institutes of Health Office of Dietary Supplements. 2024. Available from
- NHS. Calcium – Vitamins and minerals [Internet]. NHS. 2020. Available from
- Alfacalcidol [Internet]. go.drugbank.com. Available from
- PubChem. Alfacalcidol [Internet]. Nih.gov. PubChem; 2025. Available from

Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.