Category- Allopathy
About BrandName
BrandName is a medicine from the vasopressin V2 receptor antagonist drug class. It is approved to treat low sodium in blood caused by heart failure, liver disease, or certain low blood conditions like syndrome of inappropriate antidiuretic hormone secretion (SIADH). It is also approved to slow kidney damage in polycystic kidney disease. BrandName works by blocking the water retention hormone, so the kidneys release more water without losing salt. Common side effects include thirst, frequent urination, dry mouth, liver problems, and dehydration. It should not be taken with grapefruit juice, as this changes how the drug works. People with liver disease, pregnancy, breastfeeding, or inability to sense thirst should avoid it. Overdose usually occurs above 300 mg and can cause severe dehydration, very high sodium levels, confusion, fainting, and liver injury.
Medicine Highlights
| Uses | 1. To treat low sodium levels in body caused due to heart failure, liver cirrhosis and SIADH (Syndrome of Inappropriate Antidiuretic Hormone secretion) 2. To treat Autosomal Dominant Polycystic Kidney Disease (ADPKD) (genetic disorder with cysts in kidneys) |
| Common Side Effects | 1. Blurred vision 2. Dry mouth 3. Flushed, dry skin 4. Frequent urination 5. Fruit-like breath odor 6. Increased hunger 7. Increased thirst 8. Increased urination 9. Increased volume of pale, dilute urine 10. Nausea 11. Stomach pain 12. Sweating 13. Thirst 14. Troubled breathing 15. Unexplained weight loss 16. Unusual tiredness or weakness |
| Additional Information | 1.It is not recommended to use this medication without a prescription 2. Patients may need regular checkups to test liver sodium and liver function changes |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | Take this medicine orally with a sip of water |
BrandName Uses
BrandName is an oral tablet belonging to vasopressin receptor antagonists. BrandName is used for the following indications:
- Low sodium levels in body caused due to heart failure, liver cirrhosis and SIADH (Syndrome of Inappropriate Antidiuretic Hormone secretion)
- Autosomal Dominant Polycystic Kidney Disease (ADPKD) (genetic disorder with cysts in kidneys)
BrandName side effects
More Common
- Blurred vision
- Dry mouth
- Flushed, dry skin
- Frequent urination
- Fruit-like breath odor
- Increased hunger
- Increased thirst
- Increased urination
- Increased volume of pale, dilute urine
- Nausea
- Stomach pain
- Sweating
- Thirst
- Troubled breathing
- Unexplained weight loss
- Unusual tiredness or weakness
Less Common
- Anxiety
- Blood in the urine
- Bloody stools
- Blue lips, fingernails, or skin
- Bruising
- Chest pain
- Confusion
- Cough
- Coughing or vomiting blood
- Dark urine
- Dizziness or lightheadedness
- Fainting
- Fast, slow, irregular, or shallow heartbeat
- Fever
- Irregular, fast or slow, or shallow breathing
- Loss of consciousness
- Muscle cramp, spasm, pain, or stiffness
- Pain, redness, or swelling in the arm or leg
- Persistent bleeding or oozing from puncture sites, mouth, or nose
- Pink or red urine
- Rash
- Rectal bleeding
- Stomach tenderness
- Troubled breathing
- Sweating
- Vaginal bleeding
How BrandName works
BrandName works by blocking a body hormone called vasopressin that normally makes the kidneys hold on to water. When this hormone is blocked, the kidneys release more water into urine without losing much salt. This helps correct low blood sodium and reduces fluid buildup in the body.
Safety Measures and Warning
Pregnancy
BrandName is not recommended during pregnancy because it may harm the baby by affecting liver and fluid balance. So, always consult your doctor before using it.
Breastfeeding
BrandName is not recommended during breastfeeding because it may pass into breast milk and affect the baby by disturbing fluid and liver balance. Always consult your doctor before use.
Kidney and Liver Problems
BrandName is not recommended for patients with serious liver problems because it can worsen liver injury. It should also be avoided or used very carefully in kidney patients with advanced failure, as it may not work and can cause dehydration. Always consult your doctor before use.
BrandName Interaction with Food Product
Avoid consuming alcohol and smoking simultaneously, as it may affect the drug’s action and show an effect on the brain, leading to severe drowsiness, sedation, and coma in severe cases.
BrandName Interaction with Other Medicines
Avoid taking BrandNamewith the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
BrandName Chemical Structure
IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name
7-chloro-5-hydroxy-2-(1,2,4-triazol-1-yl)-1-(4-tert-butylphenyl)-3-(2-methylbenzoyl)indole

Intake routine/cycle
Daily dose
Take BrandName exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
Missed Dose
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Overdose
It is not recommended to take more than 300 mg of BrandName per day, as it may cause severe overdosing effects like extreme dehydration, drowsiness, confusion, unconsciousness, sweating, double vision, low blood pressure, and slurred speech. Immediately seek medical attention and meet the doctor if necessary.
Storage
- Store the medicine at room temperature.
- Keep away from sunlight and moisture
- Keep out of reach of children
Directions for use
- TakeBrandName exactly as prescribed by your doctor, at the same time each day.
- Do not stop taking BrandName without your doctor’s approval, even if you feel better.
- If you forget to take the BrandName, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose.
FAQ’s
What are the uses of BrandName tablets?
BrandName tablets are used to treat low sodium levels in the blood caused by conditions like heart failure, liver disease, or SIADH. They are also approved to slow kidney damage in adults with polycystic kidney disease.
What are the side effects of BrandName tablets?
Common side effects of BrandName tablets include thirst, frequent urination, dry mouth, constipation, and weakness. Serious side effects can include liver injury, dehydration, dizziness, fainting, and very high sodium levels in the blood. Always consult your doctor if you notice unusual symptoms while taking this medicine.
What is the drug class of BrandName?
BrandName belongs to the vasopressin V2 receptor antagonist drug class. This means it blocks the action of vasopressin, a hormone that normally makes the kidneys hold on to water, helping the body get rid of excess fluid while keeping sodium levels balanced.
What is the importance of BrandName in heart diseases?
BrandName is important in heart diseases because it helps manage low blood sodium levels that often occur in heart failure. By removing excess water without losing sodium, it reduces fluid overload, improves symptoms, and supports better electrolyte balance in these patients.
Reference
- Mayo Clinic. Tolvaptan 30 mg (oral route) – Side effects & dosage [Internet]. Rochester (MN): Mayo Foundation for Medical Education and Research; c2025 [cited 2026 Jan 20]. Available from.
- National Center for Biotechnology Information. PubChem Compound Summary for CID 213097, Tolvaptan 30 mg [Internet]. Bethesda (MD): National Library of Medicine; c2004–2026 [cited 2026 Jan 20]. Available from.
- Drugs.com. Tolvaptan 30 mg: Uses, Dosage, Side Effects [Internet]. Drugs.com; c1996–2026 [cited 2026 Jan 20]. Available from.
- National Center for Biotechnology Information. Tolvaptan 30 mg [Internet]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan– [cited 2026 Jan 20]. Available from.

Siva Krishna Adithya Bhumireddy completed a Bachelor of Pharmacy from GIET School of Pharmacy, affiliated with Andhra University, and from his 3rd year of graduation, he was working as a freelance medical and publication writer. Having expertise in systematic reviews and clinical research. With his keen interest and skills in research and documentation practices, he also reviewed more than 150 manuscripts from international journals like Elsevier, Springer Nature, and Sage Journals, and all the manuscripts were indexed and appeared in PubMed, Scopus, and Web of Science databases, and he received honorary recognition letters and certificates from all of them. Siva Krishna Adithya also published a few systematic, narrative reviews and a few chapters of international expertise.