Category- Allopathy
About Dicyclomine and Dimethicone Syrup
This medicine contains dicyclomine and dimethicone. Dicyclomine is an antispasmodic medicine that relaxes the muscles of the stomach and intestines, helping relieve abdominal cramps and spasms. Dimethicone is an anti-foaming agent that breaks gas bubbles in the stomach and intestines, reducing bloating, fullness, and discomfort caused by excess gas.
Common side effects include dry mouth, dizziness, nausea, blurred vision, constipation, and drowsiness. Some people may also experience mild stomach discomfort or headaches. Rarely, serious allergic reactions, difficulty passing urine, or severe dizziness may occur and require immediate medical attention.
Taking more than the recommended dose may cause severe drowsiness, confusion, blurred vision, rapid heartbeat, difficulty breathing, or seizures. Seek immediate medical attention in case of an overdose.
Medicine Highlights
| Uses | 1. To relieve abdominal cramps and stomach pain 2. To treat intestinal and stomach muscle spasms 3. To reduce bloating and excess gas 4. To relieve discomfort associated with irritable bowel syndrome (IBS) |
| Common Side Effects | 1. Dry mouth 2. Dizziness 3. Drowsiness 4. Nausea 5. Constipation 6. Blurred vision |
| Additional Information | To keep you safe and healthy, use this medicine only with your doctor’s guidance. |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | Take this syrup orally with a measuring spoon. |
Dicyclomine and Dimethicone Syrup Uses
Dicyclomine and Dimethicone Syrup is used to treat the following conditions:
- Abdominal cramps
- Irritable bowel syndrome (IBS)
- Stomach and intestinal spasms
- Gas, bloating, and flatulence
- Abdominal discomfort caused by excess gas
Dicyclomine and Dimethicone Syrup side effects
More Common
- Dry mouth
- Dizziness
- Drowsiness
- Nausea
- Constipation
- Blurred vision
Less Common
- Headache
- Difficulty passing urine
- Fast heartbeat
- Skin rash
- Confusion (especially in older adults)
How Dicyclomine and Dimethicone Syrup work
This medicine combines dicyclomine and dimethicone to relieve stomach discomfort. Dicyclomine relaxes the smooth muscles of the stomach and intestines, reducing painful muscle spasms and cramps. Dimethicone breaks up gas bubbles in the digestive tract, making it easier to pass gas and relieve bloating, fullness, and abdominal discomfort.
Safety Measures and Warning
Allergy/Hypersentivity
Do not use this medicine if you are allergic to dicyclomine or dimethicone. Always inform your doctor before using it.
Kidney Disease
If you have kidney disease, inform your doctor before using this medicine, as reduced kidney function may increase the risk of side effects.
Glaucoma
If you have glaucoma, inform your doctor before using this medicine, as dicyclomine may increase pressure inside the eye and worsen your condition.
Urinary Retention
If you have difficulty passing urine or urinary retention, inform your doctor before taking this medicine, as dicyclomine may make it harder to urinate.
Intestinal Blockage
If you have an intestinal blockage or bowel obstruction, inform your doctor before using this medicine, as it may slow bowel movement and worsen the blockage.
Myasthenia Gravis
If you have myasthenia gravis, inform your doctor before using this medicine, as dicyclomine may worsen muscle weakness.
Liver Disease
If you have liver disease, inform your doctor before taking this medicine, as your doctor may need to monitor your treatment or adjust the dose.
Heart Problems
If you have heart disease, inform your doctor before taking this medicine, as dicyclomine may increase your heart rate and require closer monitoring.
Pregnancy and Breastfeeding
Use this medicine during pregnancy or breastfeeding only if recommended by your doctor.
Children
Do not use this medicine in infants younger than 6 months unless specifically prescribed, as serious side effects may occur.
Dicyclomine and Dimethicone Syrup Interaction with Food Product
There are no known significant food interactions with this medicine. It may be taken with or without food, as advised by your doctor. Avoid alcohol while taking this medicine, as it may increase dizziness and drowsiness.
Dicyclomine and Dimethicone Syrup Interaction with Other Medicines
Avoid taking Dicyclomine and Dimethicone Syrup with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Dicyclomine and Dimethicone Syrup Chemical Structure
IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name
Dicyclomine: 2-(diethylamino) ethyl 1-cyclohexylcyclohexane-1-carboxylate

Dimethicone: poly(dimethylsiloxane)

Intake routine/cycle
Daily dose
Take Dicyclomine and Dimethicone Syrup exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
Missed Dose
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Overdose
It is not recommended to take more than the prescribed dose of Dicyclomine 10 mg + Dimethicone 40 mg /5 ml Syrup. Overdose may cause severe stomach pain, nausea, vomiting, dizziness, drowsiness, stomach bleeding, kidney problems, or liver damage. Seek immediate medical attention if overdose symptoms occur.
Storage
- Store the medicine at room temperature.
- Keep away from sunlight and moisture.
- Keep out of reach of children
Directions for use
- Take Dicyclomine and Dimethicone Syrup exactly as prescribed by your doctor, at the same time each day.
- Do not stop taking Dicyclomine and Dimethicone Syrup without your doctor’s approval, even if you feel better.
- If you forget to take Dicyclomine and Dimethicone Syrup, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose.
FAQ’s
What are the uses of Dicyclomine and Dimethicone Syrup?
Dicyclomine and Dimethicone Syrup is used to relieve stomach cramps, abdominal pain, bloating, and excess gas. It relaxes the muscles of the stomach and intestines while helping trapped gas pass more easily, providing relief from digestive discomfort and irritable bowel syndrome (IBS).
What is Dicyclomine syrup used for children?
Dicyclomine syrup may be prescribed to children to relieve stomach cramps and intestinal spasms caused by certain digestive conditions. It should only be used under a doctor’s supervision and is not recommended for infants younger than 6 months.
What are the side effects of Dimethicone?
Dimethicone is generally well tolerated and rarely causes side effects. Some people may experience mild nausea, constipation, or an allergic skin rash. Consult with your doctor if any side effects persist or become severe.
What are the side effects of Dicyclomine?
Common side effects of dicyclomine include dry mouth, dizziness, drowsiness, blurred vision, constipation, and nausea. These are usually mild but consult your doctor if they are severe or do not go away.
What is the drug class for Dicyclomine?
Dicyclomine belongs to the antispasmodic (anticholinergic) class of medicines. It works by relaxing the muscles of the stomach and intestines to relieve abdominal cramps, spasms, and pain.
Reference
- Dicyclomine Dosage Guide + Max Dose, Adjustments [Internet]. Drugs.com. Available from
- Dicyclomine – Mechanism, Indication, Contraindications, Dosing, Adverse Effect, Interaction, Hepatic Dose | Drug Index | Pediatric Oncall [Internet]. Available from
- Dicyclomine tablets or capsules [Internet]. Cleveland Clinic. Available from
- Dicyclomine: 7 things you should know [Internet]. Drugs.com. Available from
- PubChem. PubChem [Internet]. Nih.gov. PubChem; 2026 [cited 2026 July 10]. Available from
- Dimethicone [Internet]. go.drugbank.com [cited 2026 July 10]. Available from

Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.