Pancrelipase, Activated Dimethicone Antacid tablets

Category- Allopathy

About Pancrelipase, Activated Dimethicone

Pancrelipase 170 mg + Activated Dimethicone 80 mg tablet is used to treat indigestion, bloating, and digestive discomfort. This combination helps improve digestion and reduces excess gas in the stomach and intestines. 

Pancrelipase is a digestive enzyme that helps break down fats, proteins, and carbohydrates for easy absorption. Activated Dimethicone works by breaking down gas bubbles in the stomach, reducing bloating and discomfort. Together, they improve digestion and provide relief from stomach fullness and gas. 

It is usually taken after food as prescribed by the doctor. Common side effects of Pancrelipase 170 mg + Activated Dimethicone 80 mg include nausea, stomach pain, diarrhea, constipation, bloating, and vomiting. Use with caution in people with pancreatitis, severe stomach disorders, pregnancy, or breastfeeding.    

Medicine Highlights

Uses 1. To treat indigestion (difficulty digesting food)   
2. To relieve stomach discomfort after meals  
3. To improve digestion in pancreatic enzyme deficiency 
Common Side Effects  1. Nausea  
2. Stomach pain  
3. Diarrhea  
4. Constipation  
5. Vomiting  
6. Abdominal discomfort
Additional Information 1. Avoid consuming alcohol and tobacco with this medicine 
2. It is usually taken once daily, preferably in the evening, or as prescribed by your doctor.
Storage 1. The medicine should be stored at room temperature.  
2. Keep away from sunlight and moisture.  
3. Keep away from the reach of children 
How to Take This MedicineThis medicine should be taken orally with a sip of water. 

Pancrelipase, Activated Dimethicone Uses

Pancrelipase 170 mg + Activated Dimethicone 80 mg is used to treat the following conditions:

  1. Indigestion (difficulty digesting food)  
  2. Pancreatic enzyme deficiency  
  3. Stomach discomfort after meals 

Pancrelipase, Activated Dimethicone side effects 

More Common

  1. Nausea  
  2. Stomach pain  
  3. Diarrhea  
  4. Constipation  
  5. Vomiting  
  6. Abdominal discomfort         

Less Common 

  1. Skin rash  
  2. Itching  
  3. Allergic reaction  
  4. Severe stomach irritation  
  5. Persistent vomiting  
  6. Breathing difficulty      

How Pancrelipase, Activated Dimethicone works 

Pancrelipase 170 mg + Activated Dimethicone 80 mg tablet works by improving digestion and reducing gas discomfort. Pancrelipase breaks down fats, proteins, and carbohydrates making it easier for your body to digest food properly and activated Dimethicone works by breaking the gas bubbles in the stomach and intestines, reducing bloating and fullness. Together, they improve digestion and relieve stomach discomfort. 

Safety Measures and Warning 

Allergy / Hypersensitivity

If you are allergic to Pancrelipase 170 mg + Activated Dimethicone 80 mg such as rash, itching, swelling, or shortness of breath, inform your doctor before taking this medicine. 

Pancreatitis

Do not take this medicine during acute pancreatitis or severe pancreatic pain unless your doctor advises it, as it may worsen the condition.

Kidney disease

People with kidney disease should use this medicine carefully and only under medical advice, as side effects may increase.

Pregnancy

Pregnant women should take this medicine only if advised by a doctor, because its safety during pregnancy is not fully known.

Breastfeeding

Breastfeeding mothers should consult a doctor before taking this medicine to avoid possible harm to the baby.

Pancrelipase, Activated Dimethicone Interaction with Food Product 

Take Pancrelipase, Activated Dimethicone after food, as it improves enzyme action and reduces stomach irritation. Avoid heavy oily meals if you have indigestion. Avoid alcohol unless your doctor says it is safe.

Pancrelipase, Activated Dimethicone Interaction with Other Medicines  

Avoid taking Pancrelipase, Activated Dimethicone with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

Pancrelipase, Activated Dimethicone Chemical Structure

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Pancrelipase: Pancrelipase 

Pancrelipase 170 mg

Dimethicone: poly(dimethylsiloxane) 

Activated Dimethicone 80 mg

Intake routine/cycle

Daily dose

Take Pancrelipase, Activated Dimethicone exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

It is not recommended to take more than the prescribed dose. Taking too much may cause nausea, vomiting, diarrhea, stomach pain, or severe abdominal discomfort. In rare cases, allergic reactions may occur. Seek immediate medical attention if any severe symptoms develop.

Storage

  1. Store the medicine at room temperature. 
  2. Keep away from sunlight and moisture. 
  3. Keep out of reach of children 

Directions for use 

  1. Take Pancrelipase, Activated Dimethicone exactly as prescribed by your doctor, at the same time each day. 
  2. Do not stop taking Pancrelipase, Activated Dimethicone without your doctor’s approval, even if you feel better. 
  3. If you forget to take Pancrelipase, Activated Dimethicone, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose.  

FAQ’s

What are the uses of Pancrelipase 170 mg + Activated Dimethicone 80 mg? 

Pancrelipase 170 mg + Activated Dimethicone 80 mg is used to treat indigestion, bloating, gas, and stomach discomfort. It also helps people with poor digestion due to low digestive enzymes by improving the breakdown of fats, proteins, and carbohydrates in food. 

What are the side effects of Pancrelipase 170 mg + Activated Dimethicone 80 mg? 

Common side effects of Pancrelipase 170 mg + Activated Dimethicone 80 mg include nausea, stomach pain, bloating, diarrhea, constipation, vomiting, and gas. Some people may also experience mild abdominal discomfort or irritation. 

What are the contraindications of Pancrelipase 170 mg + Activated Dimethicone 80 mg? 

Pancrelipase 170 mg + Activated Dimethicone 80 mg should not be used in people who are allergic to pancrelipase, dimethicone, or any of its ingredients. It should also be avoided in acute pancreatitis or severe pancreatic inflammation unless advised by a doctor, as it may worsen the condition. 

Reference  

  1. Welcome To Zscaler Directory Authentication [Internet]. Nih.gov. 2025. Available from 
  2. PubChem. Dimethicone [Internet]. pubchem.ncbi.nlm.nih.gov. Available from 
  3. Lewsley J. What is dimethicone? Uses, safety, and alternatives [Internet]. 2022. Available from        

Authors

  • Pranathi Chintaluri

    Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children's health” which will be published by the end of 2025.

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  • Mahak Phartyal

    Mahak Phartyal completed her bachelor's in pharmacy from Veer Madho Singh Bhandari Uttarakhand Technical University. She previously worked as a Medical Writer at Meril Life Sciences, where she wrote numerous scientific abstracts for conferences such as India Live 2024 and the European Society of Cardiology (ESC). During her college years, she developed a keen research interest and published an article titled “Preliminary Phytochemical Screening, Physicochemical and Fluorescence Analysis of Nyctanthes arbor-tristis and Syzygium cumini Leaves.

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