Category- Allopathy
About Aceclofenac 100 mg + Tizanidine 2 mg
Aceclofenac 100 mg + Tizanidine 2 mg tablet is used to relieve pain, inflammation, muscle stiffness, and muscle spasms associated with conditions such as acute musculoskeletal pain, low back pain, neck pain, cervical spondylosis, sprains, strains, sports injuries, and other painful muscle disorders. This medicine consists of active ingredients such as aceclofenac and tizanidine, where aceclofenac works by blocking the production of certain chemicals (prostaglandins) that cause pain and inflammation, while tizanidine acts as a muscle relaxant by reducing nerve signals responsible for muscle tightness and spasms, thereby improving movement and reducing discomfort.
The dose should be taken exactly as prescribed by a doctor. Do not take more than the recommended dose or use it for longer than advised.
Common side effects include drowsiness, dizziness, dry mouth, stomach pain, nausea, indigestion, weakness, and headache. In rare cases, it may cause stomach ulcers, gastrointestinal bleeding, severe allergic reactions, liver problems, low blood pressure, or severe drowsiness that require immediate medical attention.
Medicine Highlights
| Uses | 1. To treat acute musculoskeletal pain 2. To relieve muscle spasms 3. To treat low back and neck pain 4. To relieve pain due to sprains and strains 5. To reduce pain and inflammation associated with sports injuries |
| Common Side Effects | 1. Drowsiness 2. Dizziness 3. Dry mouth 4. Stomach pain 5. Nausea 6. Indigestion 7. Weakness 8. Headache |
| Additional Information | To keep you safe and healthy, use this medicine only with your doctor’s guidance. |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | Take this medication orally with a sip of water. |
Aceclofenac 100 mg + Tizanidine 2 mg Uses
Aceclofenac 100 mg + Tizanidine 2 mg is an oral medicine. It is used for following indications:
- Acute musculoskeletal pain
- Muscle spasms
- Low back pain
- Neck pain
- Sprains and strains
- Sports injuries and painful muscle conditions
Aceclofenac 100 mg + Tizanidine 2 mg side effects
More Common
- Drowsiness
- Dizziness
- Dry mouth
- Stomach pain
- Nausea
- Indigestion
- Weakness
- Headache
Less Common
- Stomach ulcer
- Gastrointestinal bleeding
- Liver function abnormalities
- Kidney problems
- Low blood pressure
- Slow heart rate
- Severe allergic reactions
- Skin rash
- Swelling of the face or throat
How Aceclofenac 100 mg + Tizanidine 2 mg work
Aceclofenac 100 mg + Tizanidine 2 mg work by relieving pain and muscle spasms. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain, swelling, and inflammation by blocking the production of prostaglandins (pain producing chemicals in the body). Tizanidine is a centrally acting muscle relaxant that reduces muscle stiffness and spasms by blocking excessive nerve impulses from the brain and spinal cord, helping muscles relax and improving mobility.
Safety Measures and Warning
Allergy/Hypersentivity
If you are allergic to aceclofenac, tizanidine, other NSAIDs, or any of the ingredients in this medicine, avoid using it. Serious allergic reactions such as rash, itching, swelling, or difficulty breathing may occur.
Stomach Disorders
If you have a history of stomach ulcers, gastrointestinal bleeding, or inflammatory bowel disease, aceclofenac may worsen these conditions. Always inform your doctor about your medical history before starting treatment.
Liver or kidney disease
Patients with liver or kidney problems may require dose adjustments. Consult your doctor before taking this medicine.
Low blood pressure
Tizanidine may lower blood pressure and cause dizziness or fainting, especially when standing up suddenly. Rise slowly from sitting or lying positions.
Aceclofenac 100 mg + Tizanidine 2 mg Interaction with Food Product
Avoid excessive alcohol consumption while taking this medicine, as it may increase the risk of stomach irritation, excessive drowsiness, dizziness, and liver damage.
Aceclofenac 100 mg + Tizanidine 2 mg Interaction with Other Medicines
Avoid taking Aceclofenac 100 mg + Tizanidine 2 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Aceclofenac 100 mg + Tizanidine 2 mg Chemical Structure
IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name
Aceclofenac: 2-[2-[2-[(2,6-dichlorophenyl) amino] phenyl] acetyl]oxyacetic acid
Tizanidine: 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine
Intake routine/cycle
Daily dose
Take Aceclofenac 100 mg + Tizanidine 2 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
Missed Dose
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Overdose
It is not recommended to take more than the prescribed dose of Aceclofenac 100 mg + Tizanidine 2 mg. Overdose may cause severe stomach pain, nausea, vomiting, dizziness, drowsiness, stomach bleeding, kidney problems, or liver damage. Seek immediate medical attention if overdose symptoms occur.
Storage
- Store the medicine at room temperature.
- Keep away from sunlight and moisture.
- Keep out of reach of children
Directions for use
- Take Aceclofenac 100 mg + Tizanidine 2 mg exactly as prescribed by your doctor, at the same time each day.
- Do not stop taking Aceclofenac 100 mg + Tizanidine 2 mg without your doctor’s approval, even if you feel better.
- If you forget to take Aceclofenac 100 mg + Tizanidine 2 mg, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose.
FAQ’s
What are the uses of Aceclofenac and Tizanidine tablets?
Aceclofenac and Tizanidine tablets are used to relieve pain, inflammation, muscle stiffness, and muscle spasms caused by conditions such as back pain, neck pain, sprains, strains, sports injuries, and other musculoskeletal disorders.
Can I take Aceclofenac and Tizanidine tablets for back pain?
Yes. Aceclofenac and Tizanidine tablets are commonly prescribed for acute lower back pain. Aceclofenac helps reduce pain and inflammation, while Tizanidine relaxes tight muscles and relieves muscle spasms.
Can I take Aceclofenac and Tizanidine tablets every day?
Take Aceclofenac and Tizanidine tablets only for the duration and dose prescribed by your doctor. Long-term or excessive use without medical supervision may increase the risk of side effects such as stomach ulcers, liver problems, kidney problems, or excessive drowsiness.
Do Aceclofenac and Tizanidine tablets cause drowsiness?
Yes. Tizanidine may cause drowsiness, dizziness, or sleepiness in some people. Avoid driving, operating heavy machinery, or consuming alcohol until you know how the medicine affects you.
Reference
- PubChem. Aceclofenac [Internet]. pubchem.ncbi.nlm.nih.gov. Available from
- Aceclofenac [Internet]. go.drugbank.com. Available from
- PubChem. Tizanidine [Internet]. pubchem.ncbi.nlm.nih.gov. Available from
- Tizanidine (Oral Route) Description and Brand Names – Mayo Clinic [Internet]. Available from
- Shirin Ghanavatian, Armen Derian. Tizanidine [Internet]. Nih.gov. StatPearls Publishing; 2019. Available from
Authors
Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.