Category- Allopathy
About Atorvastatin 20 mg + Ezetimibe 10 mg
Atorvastatin 20 mg + Ezetimibe 10 mg (EC) tablet is used to treat high cholesterol and blood fats. Atorvastatin blocks the production of bad cholesterol, whereas ezetimibe blocks the absorption of cholesterol from food. Common side effects of Atorvastatin 20 mg + Ezetimibe 10 mg tablet are tiredness, stomach upset, or muscle pain and, rarely, serious muscle damage. It’s not safe for those with liver, kidney, or gallbladder issues during pregnancy. Avoid alcohol and take vitamin K-rich foods with care because it can increase the drug effects and can cause internal bleeding. Take this medication after food to get the maximum effect. Taking more than 200 mg of this medication per day can cause internal bleeding, liver and kidney damage, sweat, and dizziness.
Medicine Highlights
| Uses | 1. To control high cholesterol levels in body 2. To improve heart health 3. To remove clogged fat in arteries 4. To treat genetically occurring (High cholesterol in blood) hypercholesterolemia (familial hypercholesterolemia) |
| Common Side Effects | 1. Chills 2. Fever 3. Itching, skin rash 4. Muscle aches and pains 5. Nausea 6. Stomach pain 7. Vomiting 8. Runny nose, sneezing; or 9. Difficulty in moving 10. Joint pain or swelling 11. Muscle pain, cramps, spasms, or stiffness |
| Additional Information | 1. Avoid consuming grapes, alcohol, and tobacco while taking this medicine. 2. This medicine is also used to prevent heart attacks and strokes. |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | Take this medicine orally with a sip of water |
Atorvastatin 20 mg + Ezetimibe 10 mg Uses
Atorvastatin 20 mg + ezetimibe 10 mg is used to treat the following indications:
- Increased levels of bad cholesterol (hypercholesterolemia)
- Clogged fat in arteries (atherosclerosis)
- Clots in blood vessels
- Genetically occurring hypercholesterolemia (familial hypercholesterolemia)
Atorvastatin 20 mg + Ezetimibe 10 mg side effects
More Common
- Chills
- Fever
- Itching, skin rash
- Muscle aches and pains
- Nausea
- Stomach pain
- Vomiting
- Runny nose, sneezing; or
- Difficulty in moving
- Joint pain or swelling
- Muscle pain, cramps, spasms, or stiffness
Less Common
- Abdominal or stomach pain
- Confusion
- Difficult breathing
- Difficulty with moving
- Irregular heartbeat
- Muscle, joint, or bone pain
- Muscle stiffness
- Muscle weakness
- Nausea or vomiting
- Nervousness
- Numbness or tingling in the hands, feet, or lips
- Weakness or heaviness of the legs
How Atorvastatin 20 mg + Ezetimibe 10 mg works
Atorvastatin 20 mg + Ezetimibe 10 mg tablet work together as a cleanup crew for your blood vessels. Atorvastatin slows down the body’s production of bad cholesterol and ezetimibe helps clear clogged arteries.
Safety Measures and Warning
Pregnancy
Ezetimibe can harm a developing fetus, with animal studies showing growth issues, and due to limited human data, it’s avoided in pregnancy. Always inform your doctor before using this medication.
Breastfeeding
Trace amounts of Atorvastatin 20 mg + Ezetimibe 10 mg tablet can pass through breast milk. Tell your health care provider if you are breastfeeding or plan to breastfeed. Inform and consult your doctor before prescribing.
Kidney and Liver Problems
Atorvastatin 20 mg + Ezetimibe 10 mg tablet can affect the liver’s functioning by causing changes in liver enzymes and can lead to severe toxicity and liver damage. So inform your doctor before taking this medication.
Atorvastatin 20 mg + Ezetimibe 10 mg Interaction with Food Product
Alcohol and smoking can interact with the Atorvastatin 10 mg + Ezetimibe 10 mg tablet, simultaneously affecting the drug’s action, and can cause an increase or decrease in the drug’s action.
Atorvastatin 20 mg + Ezetimibe 10 mg Interaction with Other Medicines
Avoid taking Atorvastatin 20 mg + Ezetimibe 10 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Atorvastatin 20 mg + Ezetimibe 10 mg Chemical Structure
IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name
Atorvastatin- (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid
Ezetimibe-(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
Intake routine/cycle
Daily dose
Take Atorvastatin 20 mg + Ezetimibe 10 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
Missed Dose
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Overdose
It is not recommended to take more than 200 mg of this medication, as it may cause severe overdosing effects like liver damage, kidney damage, pancreatitis, muscle problems, nausea, and muscle problems. If you face any of the severe effects, consult the doctor.
Storage
- Store the medicine at room temperature.
- Keep away from sunlight and moisture.
- Keep out of reach of children
Directions for use
- Take Atorvastatin 20 mg + Ezetimibe 10 mg exactly as prescribed by your doctor, at the same time each day.
- Do not stop taking Atorvastatin 20 mg + Ezetimibe 10 mg without your doctor’s approval, even if you feel better.
- If you forget to take the Atorvastatin 20 mg + Ezetimibe 10 mg, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose.
FAQ’s
What are the uses of the atorvastatin 20 mg and ezetimibe 10 mg combination medicine?
Atorvastatin 20 mg + ezetimibe 10 mg is an oral medicine belonging to the category of lipid-lowering drugs and is used for the treatment of Increased levels of bad cholesterol (hypercholesterolemia) and Clogged fat in arteries (atherosclerosis).
What is the price of atorvastatin and ezetimibe tablets?
At Saya Care, atorvastatin 20 mg + ezetimibe 10 mg costs 31 rupees for 10 tablets. They are used to control fat and cholesterol in the body and to improve heart health.
What is the Atorvastatin 20 mg + Ezetimibe 10 mg drug class?
Atorvastatin 20 mg + Ezetimibe 10 mg belongs to the drug class of angiotensin receptor blockers and thiazide diuretics and can show vascular effects.
What is the mechanism of action of atorvastatin and ezetimibe?
Atorvastatin and ezetimibe are medicines that work together to lower harmful cholesterol and blood fats. This may cause side effects like tiredness, stomach upset, or muscle pain and, rarely, serious muscle damage.
Reference
- The Health Site. How to lower cholesterol in one week: 10 Indian foods to lower cholesterol naturally at home. TheHealthSite.com. 2024 [cited 2024 Nov 2]. Available from.
- Hoogwerf BJ. Statins may increase diabetes, but benefit still outweighs risk. Cleveland Clinic Journal of Medicine. 2023 Jan 3;90(1):53-62. Available from.
- Healthline. Atorvastatin oral tablet: uses, dosage, and side effects [Internet]. Healthline; 2023 [cited 2025 Jan 3]. Available from.
- NHS. How and when to take atorvastatin [Internet]. 2023 [cited 2025 Jan 3]. Available from.
- Kanaki AI, Sarafidis PA, Georgianos PI, Stafylas PC, Kanavos K, Tziolas IM, Lasaridis AN. Low-dose atorvastatin reduces ambulatory blood pressure in patients with mild hypertension and hypercholesterolaemia: a double-blind, randomized, placebo-controlled study. J Hum Hypertens. 2012 Oct;26(10):577-84. doi: 10.1038/jhh.2011.80. Epub 2011 Sep 1. PMID: 21881597. Available from.
- PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 150311, Ezetimibe; [cited 2026 Apr. 8]. Available from.
- Mayo Clinic. Atorvastatin and ezetimibe (oral route) – Side effects & dosage. Mayo Clinic [Internet]. 2026 Mar 31 [cited 2026 Apr 8]. Available from.
Authors
Siva Krishna Adithya Bhumireddy completed a Bachelor of Pharmacy from GIET School of Pharmacy, affiliated with Andhra University, and from his 3rd year of graduation, he was working as a freelance medical and publication writer. Having expertise in systematic reviews and clinical research. With his keen interest and skills in research and documentation practices, he also reviewed more than 150 manuscripts from international journals like Elsevier, Springer Nature, and Sage Journals, and all the manuscripts were indexed and appeared in PubMed, Scopus, and Web of Science databases, and he received honorary recognition letters and certificates from all of them. Siva Krishna Adithya also published a few systematic, narrative reviews and a few chapters of international expertise.