Category- Allopathy
About Metoprolol 25 mg + Cilnidipine 10 mg
Metoprolol 25 mg + Cilnidipine 10 mg tablet consists of metoprolol and cilnidipine and is used to prevent strokes and heart attacks. Common side effects include rapid weight gain, shortness of breath, slow or uneven heartbeat, and numbness or a cold feeling in your hands and feet.Use the medicine as directed. Do not take more than 40 mg of this medicine in a day. If it’s taken more than 40 mg per day, it causes severe fall in BP leading to fainting and unconsciousness; sometimes it may be fatal. Metoprolol 25 mg + Cilnidipine 10 mg should be taken before or after food.
Medicine Highlights
| Uses | 1. To treat high blood pressure 2. To prevent heart attacks. |
| Common Side Effects | 1. Urination 2. Dizziness 3. Headache 4. Fatigue 5. Nausea 6. Constipation 7. Hypokalemia 8. Photosensitivity 9. Gout 10. Hyperglycemia |
| Additional Information | 1. Take medicine every day at the same time to maintain the drug well in the blood. 2. Do not stop the medicine usage suddenly |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | Take this medicine orally with a sip of water |
Metoprolol 25 mg + Cilnidipine 10 mg Uses
Metoprolol 25 mg + cilnidipine 10 mg tablet is used to treat the following indications:
- High blood pressure (Hypertension)
- Prevent sudden spike in blood pressure
- Risk of heart attack in patients with high blood pressure.
Metoprolol 25 mg + Cilnidipine 10 mg side effects
More Common
- Dizziness
- Swelling in your legs
- Slow heartbeats
- Tiredness
- Headache
Less Common
- A light-headed feeling, like you might pass out
- Rapid weight gain
- Shortness of breath
- Slow or uneven heartbeats
- Numbness or cold feeling in your hands and feet
How Metoprolol 25 mg + Cilnidipine 10 mg works
Metoprolol 25 mg + Cilnidipine 10 mg works by reducing the load on heart and reducing blood pressure in the body.
Safety Measures and Warning
Allergy or Hypersensitivity
Patients with allergies should not take this medicine due to problems like severe low BP that may arise. Consult a doctor before taking the medicine.
Breastfeeding
Metoprolol 25 mg + Cilnidipine 10 mg is not usually recommended during breastfeeding because there is no reliable information on whether it passes into breast milk or how it might affect a nursing infant. So, consult a doctor before using it.
Heart Problems
If patients with heart disease, like those with a slow heart rate, take this medicine, it may cause low blood pressure and heart attack. Recommended to take the medicine only by doctors’ prescription.
Pregnancy
Metoprolol 25 mg + Cilnidipine 10 mg is not usually recommended during pregnancy because there is no reliable information on its safety on fetus. So, consult a doctor before using it.
Metoprolol 25 mg + Cilnidipine 10 mg Interaction with Food Product
Avoid consuming alcohol and smoking simultaneously together, as it may affect the drug’s action and show an effect on the brain, leading to severe drowsiness, sedation, and coma in severe cases.
Metoprolol 25 mg + Cilnidipine 10 mg Interaction with Other Medicines
Avoid taking Metoprolol 25 mg + Cilnidipine 10 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Metoprolol 25 mg + Cilnidipine 10 mg Chemical Structure
IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name
Metoprolol- 1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol

Cilnidipine-3-O-(2-methoxyethyl) 5-O-[(E)-3-phenylprop-2-enyl] 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Intake routine/cycle
Daily dose
Take Metoprolol 25 mg + Cilnidipine 10 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
Missed Dose
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Overdose
It is not recommended to take more than 100 mg of Metoprolol + Cilnidipine per day, as it may cause severe overdosing effects like extreme drowsiness, confusion, unconsciousness, sweating, double vision, low blood pressure, and slurred speech. Immediately seek medical attention and meet the doctor if necessary.
Storage
- Store the medicine at room temperature.
- Keep away from sunlight and moisture.
- Keep out of reach of children
Directions for use
- Take Metoprolol 25 mg + Cilnidipine 10 mg exactly as prescribed by your doctor, at the same time each day.
- Do not stop taking Metoprolol 25 mg + Cilnidipine 10 mg without your doctor’s approval, even if you feel better.
- If you forget to take Metoprolol 25 mg + Cilnidipine 10 mg, take them as soon as you remember. If it’s almost time for your next dose, skip the missed dose.
FAQ’s
What are the uses of Metoprolol 25 mg + Cilnidipine 10 mg tablets?
Metoprolol 25 mg + Cilnidipine 10 mg is commonly used to treat High Blood pressure and heart attacks.
What are the side effects of Metoprolol 25 mg + Cilnidipine 10 mg tablets?
Metoprolol 25 mg + Cilnidipine 10 mg side effects include severe bradycardia, irregular heartbeat, and low blood pressure.
Where can I buy Metoprolol 25 mg + Cilnidipine 10 mg online?
You can buy Metoprolol 25 mg + Cilnidipine 10 mg from SayaCare at an 80% discount. They test every batch of the medicine and publish the test reports on their website, providing you with safe, verified medicine delivered right to your doorstep.
What is the maximum dose of cilnidipine per day?
The maximum dose of cilnidipine to be taken per day is 20 mg. Taking of excessive doses causes a severe fall in BP and causes fainting.
Reference
- Drugs.com. Metoprolol Monograph [Internet]. Drugs.com; c2000–2025 [cited 2025 Jun 25]. Available from.
- National Center for Biotechnology Information. PubChem Compound Summary for CID 5311057, Cilnidipine [Internet]. Bethesda (MD): National Library of Medicine (US); [cited 2025 Jun 25]. Available from.
- National Center for Biotechnology Information. PubChem Compound Summary for CID 71301, Metoprolol [Internet]. Bethesda (MD): National Library of Medicine (US); [cited 2025 Jun 25]. Available from.
- Li X, Wang C, Li T, Liu Y, Liu S, Tao Y, Ma Y, Gao X, Cao Y. Bioequivalence of cilnidipine tablets in healthy Chinese subjects: a single-dose and two-period crossover randomized study. BMC Pharmacol Toxicol. 2020 Nov 19;21(1):80. Available from.
- National Center for Biotechnology Information. PubChem Compound Summary for CID 115193, S-Cilnidipine. Bethesda (MD): National Library of Medicine (US). Available from.
- Cerner Multum. Cilnidipine: Uses, Side Effects & Warnings [Internet]. Drugs.com; 2025 Mar 7 [cited 2026 Feb 3]. Available from.

Siva Krishna Adithya Bhumireddy completed a Bachelor of Pharmacy from GIET School of Pharmacy, affiliated with Andhra University, and from his 3rd year of graduation, he was working as a freelance medical and publication writer. Having expertise in systematic reviews and clinical research. With his keen interest and skills in research and documentation practices, he also reviewed more than 150 manuscripts from international journals like Elsevier, Springer Nature, and Sage Journals, and all the manuscripts were indexed and appeared in PubMed, Scopus, and Web of Science databases, and he received honorary recognition letters and certificates from all of them. Siva Krishna Adithya also published a few systematic, narrative reviews and a few chapters of international expertise.