Paracetamol 325 mg + Dicyclomine hcl 20 mg

Category- Allopathy

About Paracetamol 325 mg + Dicyclomine hcl 20 mg

Paracetamol 325 mg + Dicyclomine HCl 20 mg is a combination medicine used to relieve abdominal pain and cramps associated with conditions such as irritable bowel syndrome, intestinal spasms, menstrual cramps, and stomach discomfort. Paracetamol works by reducing pain and fever, while dicyclomine relaxes the muscles of the stomach and intestines to relieve spasms. 

Common side effects include dry mouth, dizziness, nausea, blurred vision, drowsiness, constipation, and headache. 

This medicine should be used exactly as prescribed by your doctor. Avoid taking more than the recommended dose, as excessive use of paracetamol may cause serious liver damage. Inform your doctor if you have liver disease, glaucoma, urinary problems, or intestinal obstruction before taking this medicine.

Medicine Highlights

Paracetamol 325 mg + Dicyclomine hcl 20 mg Uses

Paracetamol 325 mg + Dicyclomine HCl 20 mg is used to treat the following conditions:

1. Abdominal and Menstrual cramps 
2. Irritable bowel syndrome (IBS)-related pain 
3. Intestinal spasms 
4. Stomach discomfort associated with muscle spasms 
5. Fever associated with painful conditions        

Paracetamol 325 mg + Dicyclomine hcl 20 mg side effects 

More Common

1. Dry mouth 
2. Dizziness 
3. Drowsiness 
4. Nausea 
5. Blurred vision 
6. Constipation 
7. Headache          

Less Common 

1. Vomiting 
2. Weakness 
3. Difficulty urinating 
4. Loss of appetite 
5. Rapid heartbeat 
6. Skin rash 
7. Confusion (especially in elderly patients)       

How Paracetamol 325 mg + Dicyclomine hcl 20 mg works 

This medicine contains paracetamol and dicyclomine hydrochloride. Paracetamol works by reducing the production of chemical messengers called prostaglandins in the brain, which are responsible for causing pain and fever. Dicyclomine works by blocking the action of acetylcholine, a chemical messenger that triggers muscle contractions in the stomach and intestines, thereby relaxing the smooth muscles and reducing spasms. Together, they help relieve abdominal pain, cramps, and discomfort while also reducing pain and fever. 

Safety Measures and Warning 

Allergy/Hypersentivity

Do not take Paracetamol 325 mg + Dicyclomine HCl 20 mg if you are allergic to paracetamol, dicyclomine, or any of its ingredients. Seek medical help if you develop rash, swelling, itching, or difficulty breathing.

Liver disease

Use with caution if you have liver problems, as paracetamol may increase the risk of liver damage. Consult your doctor before using it.

Glaucoma

If you have glaucoma, take this medicine only under medical supervision, as dicyclomine may increase eye pressure.

Urinary problems

Consult your doctor before taking this medicine if you have difficulty passing urine or an enlarged prostate, as dicyclomine may worsen these conditions.

Pregnancy

Use this medicine during pregnancy only if advised by your doctor. Consult with your doctor before taking it.

Breastfeeding

Avoid using this medicine while breastfeeding unless recommended by your doctor, as dicyclomine may pass into breast milk.

Paracetamol 325 mg + Dicyclomine hcl 20 mg Interaction with Food Product 

Food does not significantly affect the action of this medicine. Avoid alcohol while taking this medicine, as it may increase the risk of liver damage and drowsiness. Maintain adequate fluid intake to help reduce dry mouth and constipation.

Paracetamol 325 mg + Dicyclomine hcl 20 mg Interaction with Other Medicines  

Avoid taking Paracetamol 325 mg + Dicyclomine hcl 20 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

Paracetamol 325 mg + Dicyclomine hcl 20 mg Chemical Structure

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Paracetamol: N-(4-hydroxyphenyl)acetamide

Dicyclomine:  2-(diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate 

Intake routine/cycle

Daily dose

Take Paracetamol 325 mg + Dicyclomine hcl 20 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

Taking excessive amounts of this medicine may cause severe nausea, vomiting, abdominal pain, dizziness, extreme drowsiness, blurred vision, rapid heartbeat, difficulty urinating, and serious liver damage. Seek immediate medical attention if an overdose is suspected.

Storage

1. Store the medicine at room temperature. 
2. Keep away from sunlight and moisture. 
3. Keep out of reach of children 

Directions for use 

1. Take Paracetamol 325 mg + Dicyclomine hcl 20 mg exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking Paracetamol 325 mg + Dicyclomine hcl 20 mg without your doctor’s approval, even if you feel better. 
3. If you forget to take Paracetamol 325 mg + Dicyclomine hcl 20 mg, take them as soon as you remember. If it’s almost time for your next dose, skip the missed dose.

FAQ’s

What are the uses of Paracetamol 325 mg + Dicyclomine hcl 20 mg tablets? 

Paracetamol 325 mg + Dicyclomine hcl 20 mg tablets are used to relieve abdominal pain and cramps caused by intestinal spasms, irritable bowel syndrome (IBS), menstrual cramps, and stomach discomfort. They also help reduce pain and fever.  

What are the side effects of Paracetamol 325 mg + Dicyclomine hcl 20 mg tablets? 

Common side effects of Paracetamol 325 mg + Dicyclomine hcl 20 mg tablets include dry mouth, dizziness, drowsiness, nausea, blurred vision, constipation, and headache. These effects are usually mild but consult your doctor if they persist or worsen.  

What are the contraindications of Paracetamol 325 mg + Dicyclomine hcl 20 mg tablets? 

Paracetamol 325 mg + Dicyclomine hcl 20 mg tablets should not be used in people who are allergic to either medicine. They are also contraindicated in patients with glaucoma, intestinal obstruction, severe ulcerative colitis, myasthenia gravis, obstructive urinary conditions, and infants below 6 months of age. Use with caution in patients with liver disease. 

Reference  

1. Dicyclomine Dosage Guide + Max Dose, Adjustments [Internet]. Drugs.com. Available from 
2. Dicyclomine – Mechanism, Indication, Contraindications, Dosing, Adverse Effect, Interaction, Hepatic Dose | Drug Index | Pediatric Oncall [Internet]. Available from 
3. Dicyclomine tablets or capsules [Internet]. Cleveland Clinic. Available from 
4. Dicyclomine: 7 things you should know [Internet]. Drugs.com. Available from 
5. NHS. Paracetamol for Adults [Internet]. NHS. NHS; 2019. Available from 
6. Ayoub SS. Paracetamol (acetaminophen): A familiar drug with an unexplained mechanism of action. Temperature [Internet]. 2021 Mar 16;8(4):351–71. Available from 
7. PubChem. Acetaminophen [Internet]. Pubchem. PubChem; 2020. Available from        

Pranathi Chintaluri

Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.