Category- Suppliments
About Levomefolic Acid, Pyridoxal and Methyl Cobalamin
This medicine contains Levomefolic acid + Pyridoxal-5-phosphate (Vitamin B6) + Methylcobalamin (Vitamin B12) and is used to treat and prevent vitamin B deficiencies, support nerve health, improve red blood cell formation, and manage diabetic neuropathy and other nerve-related disorders.
Levomefolic acid is an active form of folate that helps produce healthy red blood cells and supports DNA synthesis. Pyridoxal-5-phosphate, the active form of Vitamin B6, helps in protein metabolism, nerve function, and neurotransmitter production. Methylcobalamin, the active form of Vitamin B12, helps repair damaged nerves, supports brain function, and promotes healthy red blood cell formation.
Common side effects include nausea, stomach discomfort, headache, diarrhea, and skin rash. These side effects are usually mild and temporary. This medicine should be used with caution in people who are allergic to any of its ingredients or have certain medical conditions. It is commonly prescribed for vitamin deficiencies, neuropathy, and neurological disorders.
Medicine Highlights
| Uses | 1. To treat vitamin B12 deficiency 2. To treat folate deficiency 3. To support nerve health 4. To manage diabetic neuropathy 5. To support red blood cell formation |
| Common Side Effects | 1. Nausea 2. Stomach discomfort 3. Headache 4. Diarrhea 5. Skin rash 6. Dizziness 7. Vomiting 8. Loss of appetite |
| Additional Information | Avoid consuming alcohol while taking this medicine, as it may reduce the absorption and effectiveness of B vitamins. |
| Storage | 1. The medicine should be stored at room temperature 2. Keep away from sunlight and moisture 3. Keep away from the reach of children |
| How to Take This Medicine | Take this medicine orally with a sip of water. |
Levomefolic Acid, Pyridoxal and Methyl Cobalamin Uses
Levomefolic Acid, Pyridoxal and Methylcobalamin are used to treat and relieve:
- Vitamin B12 deficiency
- Folate deficiency
- Diabetic neuropathy
- Peripheral neuropathy
- Nerve pain and nerve damage
Levomefolic Acid, Pyridoxal and Methyl Cobalamin side effects
More Common
- Nausea
- Stomach discomfort
- Headache
- Diarrhea
- Vomiting
- Dizziness
- Loss of appetite
Less Common
- Skin rash
- Itching
- Allergic reactions
- Tingling sensation
- Difficulty sleeping
How Levomefolic Acid, Pyridoxal and Methyl Cobalamin works
Levomefolic Acid, Pyridoxal and Methylcobalamin work together to support healthy nerve function, improve vitamin B levels, and promote red blood cell production. Levomefolic acid provides the active form of folate needed for DNA synthesis and healthy blood cell formation. Pyridoxal-5-phosphate supports nerve signaling, protein metabolism, and neurotransmitter production. Methylcobalamin repairs damaged nerves, improves nerve conduction, and helps produce healthy red blood cells. Together, they help reduce nerve damage, improve neurological function, and correct vitamin deficiencies.
Levomefolic Acid, Pyridoxal and Methyl Cobalamin Interaction with Other Medicines
Avoid taking Levomefolic Acid, Pyridoxal and Methyl Cobalamin with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Levomefolic Acid, Pyridoxal and Methyl Cobalamin Interaction with Food Product
There are no major food restrictions while taking this medicine. Eat a balanced diet rich in vitamin B for better results. Avoid excessive alcohol consumption, as it can reduce vitamin absorption.
Intake routine/cycle
Daily dose
Take this medicine exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
Missed Dose
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Recommended Dietary Allowance (RDA)
Folate (Vitamin B9)
The recommended daily intake of folate for children is 150–300 mcg/day depending on age. Adult men and women require 400 mcg/day. Pregnant women require 600 mcg/day, and breastfeeding women require 500 mcg/day.
Pyridoxine (Vitamin B6)
The recommended daily intake of vitamin B6 for children is 0.5–1 mg/day depending on age. Adult men require 1.3–1.7 mg/day, while adult women require 1.3–1.5 mg/day. Pregnant women require 1.9 mg/day, and breastfeeding women require 2 mg/day.
Methyl cobalamin (Vitamin B12)
The recommended daily intake of vitamin B12 for children is 0.9–1.8 mcg/day depending on age. Adult men and women require 2.4 mcg/day. Pregnant women require 2.6 mcg/day, and breastfeeding women require 2.8 mcg/day.
Natural Source of Levomefolic Acid, Pyridoxal and Methyl Cobalamin
Folate (Vitamin B9)
Folate is found in spinach, broccoli, asparagus, beans, lentils, citrus fruits, avocados, and fortified cereals.
Pyridoxine (Vitamin B6)
Vitamin B6 is found in chicken, fish, bananas, potatoes, chickpeas, whole grains, eggs, and fortified cereals.
Methyl cobalamin (Vitamin B12)
Vitamin B12 is found in fish, meat, eggs, milk, cheese, yogurt, poultry, and fortified breakfast cereals.
FAQ’s
In which foods are folic acid found?
Folic acid is found in spinach, methi (fenugreek leaves), broccoli, citrus fruits, and chana (chickpeas).
Can folic acid tablets be taken during pregnancy?
Yes. Folic acid tablets are recommended during pregnancy to support the baby’s brain and spine development and to help prevent birth defects.
Which vitamin is called folic acid?
Folic acid is a form of Vitamin B9.
What are the uses of methyl cobalamin?
Methyl cobalamin is used to treat and prevent vitamin B12 deficiency. It helps make healthy red blood cells, improves anemia, and supports nerve health.
Which food contains methyl cobalamin?
Methyl cobalamin is found in meat, fish, chicken, eggs, milk, curd, cheese, and fortified cereals.
What drug class does methyl cobalamin belong to?
Methyl cobalamin belongs to the vitamin B12 supplement class. It is also called a hematinic or nutritional supplement.
Which food contains Pyridoxine?
Pyridoxine is found in foods like bananas, chicken, fish, potatoes, whole grains, nuts, and seeds.
What is Pyridoxine also known as?
Pyridoxine is also known as Vitamin B6.
Reference
- WebMD. Folic Acid: Uses, Side Effects, Interactions, Dosage, and Warning [Internet]. Webmd.com. 2009. Available from
- Entringer S. Folic Acid: Uses, Benefits & Side Effects [Internet]. Drugs.com. 2021. Available from
- Methylcobalamin – an overview | ScienceDirect Topics [Internet]. www.sciencedirect.com. Available from
- National Institutes of Health. Office of Dietary Supplements – Vitamin B6 [Internet]. Nih.gov. 2023. Available from
- WebMD. Pyridoxine (Vitamin B6): Uses, Side Effects, Interactions, Dosage, and Warning [Internet]. Webmd.com. 2019. Available from
- Pyridoxine [Internet]. go.drugbank.com. Available from
Authors
Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.