Category- Suppliments
About Alfacalcidol 0.25 mcg Tablet
Alfacalcidol 0.25 mcg Tablet is a vitamin D analogue, used to treat vitamin D deficiency and conditions related to low calcium levels, especially in patients with kidney problems. It helps improve calcium absorption from food and maintains proper calcium levels in the blood, which is important for healthy bones and muscles. It is commonly used in osteoporosis, rickets, osteomalacia, and hypocalcemia. The medicine is generally well tolerated, but excess use can lead to high calcium levels causing symptoms like nausea, vomiting, weakness, or confusion. It should be used carefully under medical supervision, especially in patients with kidney disease or those taking calcium supplements.
Medicine Highlights
| Uses | 1. To treat calcium deficiency in the body 2. To treat vitamin D deficiency 3. To treat osteoporosis 4. To treat rickets and osteomalacia (weak or soft bones) |
| Common Side Effects | 1. Nausea 2. Vomiting 3. Loss of appetite 4. Constipation 5. Increased calcium levels (hypercalcemia) 6. Weakness or tiredness |
| Additional Information | Alfacalcidol is a form of vitamin D that helps the body absorb calcium and maintain strong bones. |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | Take this medicine orally with a sip of water. |
Alfacalcidol 0.25 mcg Tablet Uses
Alfacalcidol 0.25 mcg Tablet is a vitamin D medicine, used to treat conditions caused due to calcium or vitamin D deficiency such as:
- Calcium deficiency
- Vitamin D deficiency
- Weak or soft bones (rickets, osteomalacia)
- Osteoporosis
Alfacalcidol 0.25 mcg Tablet side effects
More Common
- Nausea
- Vomiting
- Constipation
- Loss of appetite
- Weakness
Less Common
- High calcium levels (hypercalcemia)
- Headache
- Confusion
- Kidney stones (rare)
How Alfacalcidol 0.25 mcg Tablet work
Alfacalcidol 0.25 mcg Tablet is converted in the body into active vitamin D. It helps the intestines absorb more calcium from food and also helps maintain proper calcium levels in the blood. This supports strong bones and normal muscle function.
Alfacalcidol 0.25 mcg Tablet Interaction with Other Medicines
Avoid taking Alfacalcidol 0.25 mcg Tablet with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Alfacalcidol 0.25 mcg Tablet Interaction with Food Product
No major food interactions. It can be taken before or after food but maintaining a balanced calcium intake is important.
Intake routine/cycle
Daily dose
Take Alfacalcidol 0.25 mcg Tablet exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
Missed Dose
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Recommended Dietary Allowance (RDA)
Alfacalcidol
Children usually require about 400–600 IU per day. Adults generally need around 600–800 IU Pregnant and breastfeeding women may need about 600–800 IU per day. Elderly people often require higher amounts, around 800–1000 IU daily. However, the exact dose may vary depending on individual health conditions, so it is best to follow a doctor’s advice.
Natural Source of Alfacalcidol 0.25 mcg Tablet
Alfacalcidol
Alfacalcidol is obtained from sunlight exposure and foods like fatty fish, egg yolk, fortified milk, and dairy products, which help maintain healthy bones and calcium levels.
FAQ’s
What are the uses of Alfacalcidol 0.25 mcg Tablet?
Alfacalcidol 0.25 mcg Tablet are used to treat vitamin D deficiency and low calcium levels in the body. They are commonly used in conditions like osteoporosis, rickets, osteomalacia, and in patients with kidney disease where calcium balance is affected.
What are the brand names of Alfacalcidol 0.25 mcg Tablet?
Alfacalcidol 0.25 mcg Tablet is available under various brand names such as One-Alpha, Alpha D3, and Alfadol, depending on the manufacturer and region.
What is the role of Alfacalcidol 0.25 mcg Tablet in osteoporosis?
In osteoporosis, Alfacalcidol 0.25 mcg tablet helps increase calcium absorption and improves bone strength. It helps slow down bone loss and reduces the risk of fractures by maintaining proper calcium levels in the body.
What is the role of Alfacalcidol 0.25 mcg Tablet in renal failure?
In renal failure, the kidneys cannot activate vitamin D properly. Alfacalcidol provides an active form of vitamin D, which helps maintain calcium balance, supports bone health, and prevents bone weakness and related complications.
Reference
- Alfacalcidol [Internet]. go.drugbank.com. Available from
- PubChem. Alfacalcidol [Internet]. Nih.gov. PubChem; 2025. Available from
- Alfacalcidol capsules (One-Alpha®) [Internet]. Cambridge University Hospitals. 2023. Available from
Authors
Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.