Fluticasone 50mcg/2ml

Category- Allopathy

Medicine Highlights

Fluticasone Uses 

Fluticasone furoate is a medicine belonging to the category of corticosteroids and is used to treat for the following conditions: 

1. Allergic Rhinitis 
2. Asthma  
3. Chronic obstructive pulmonary disease (COPD) 
4. Allergic bronchitis  

Directions for use

1. Wash your hands before handling the respule. 
2. Open the respule and pour the contents into the nebulizer cup. 
3. Assemble the nebulizer according to the instructions. 
4. Sit upright in a comfortable position. 
5. Place the mouthpiece in your mouth or use a mask over your nose and mouth. 
6. Turn on the nebulizer and breathe in the mist slowly and deeply until the medicine is finished (usually 5–10 minutes). 
7. Rinse your mouth with water after the session to reduce throat irritation. 
8. Clean the nebulizer after each use as per instructions. 

Fluticasone side effects 

More Common  

1. Sore throat  
2. Signs of nasal damage (such as pain, severe nosebleeds, a constant whistling sound from your nose) 
3. Facial pain 
4. Eye pain 
5. White patches in your nose/back of your throat 
6. Painful swallowing 

Less Common

1. Allergic reaction (rash, swelling, difficulty breathing) 
2. Vision changes (blurred vision, glaucoma, cataract on long-term use) 
3. Suppression of adrenal gland function  
4. Slow growth in children 

How Fluticasone works 

Fluticasone furoate is a steroid that helps relieve allergy symptoms by blocking the release of certain chemical messengers in the body, such as histamines and prostaglandins. These messengers are released by immune cells when the body reacts to allergens like dust, pollen. They cause inflammation, leading to redness, swelling, sneezing, and a runny nose. By stopping these chemicals, Fluticasone reduces irritation and helps you breathe more comfortably. 

Safety Measures and Warning 

Allergy/hypersensitivity

Avoid taking this medication if you have a known allergy to fluticasone furoate. If you experience symptoms like rash, swelling, or difficulty breathing, seek immediate medical attention. 

Pregnancy

Fluticasone Furoate should be used during pregnancy only if clearly needed and prescribed by a doctor, as its safety in pregnant women is not fully established. 

Children

If used for a long time, steroids like Fluticasone may slow down growth in children. That’s why a doctor should always decide the dose and monitor regularly. 

Lung infections

Fluticasone reduces the body’s immune response in the lungs. If a person already has an infection, the medicine may make it worse instead of better. 

Tuberculosis

Since Fluticasone weakens local immunity in the lungs, TB bacteria can grow more easily. It can cause TB symptoms to worsen or reactivate a hidden TB infection.

Fluticasone Interaction with Food Product

Fluticasone inhaler has no major food interactions and can be used with your regular meals. But try to avoid grapefruit or grapefruit juice, as it can increase the medicine levels in your body and may cause side effects. 

Fluticasone Interaction with Other Medicines

Avoid taking fluticasone furoate with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal: 

Fluticasone Chemical Structure

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid, S-(fluoromethyl) ester 2-furoate.   

Intake routine/cycle

Daily dose

Take Fluticasone exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor. 

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage. 

Overdose

Don’t take more than 55 mcg/spray at each nostril fluticasone furoate in a day, as it may cause severe adverse effects due to overdosing of fluticasone furoate like darkening of the skin, fainting, loss of appetite, mental depression, unusual tiredness or weakness. 

Storage

1. Store the medicine at room temperature 
2. Keep away from sunlight and moisture 
3. Keep out of reach of children 

Fluticasone Summary 

Fluticasone furoate is an inhaled corticosteroid used for the long-term management of asthma and chronic obstructive pulmonary disease (COPD). Fluticasone furoate in general used to treat asthma, COPD, and allergic airway inflammation. It suppresses inflammation by stopping the release of inflammatory chemicals from cells like mast cells, eosinophils, and macrophages, which helps reduce airway swelling, mucus, and irritation.  

Common side effects include sore throat, hoarseness, cough, oral thrush, and headache, while rare but serious effects may include allergic reactions, vision changes, adrenal suppression with prolonged use, and slowed growth in children. It is not an emergency medication and should be inhaled regularly as prescribed. Rinsing the mouth after inhalation helps reduce the risk of oral thrush, and caution is advised in patients with untreated infections or tuberculosis. It may also be combined with long-acting bronchodilators for better control in asthma or COPD. 

FAQ’s

What are the side effects of fluticasone furoate? 

Fluticasone furoate nasal spray side effects include headache, nosebleeds, nasal ulceration, breathlessness, dry or irritated nose or throat, change in taste or smell 

What are the uses of fluticasone furoate? 

Fluticasone furoate is a steroid nasal spray used to treat nose allergies, blocked nose, sneezing, runny nose, sinus pressure, nose growths (with other medicines), and mild sinus infection symptoms. 

What is the price of fluticasone furoate nasal spray? 

The price for one bottle generally ranges from ₹160 to ₹425, depending on the branded version. At SayaCare we provide test reports with each medicine, also at SayaCare we provide you with up to 80% less cost than the market. 

What is the mechanism of action of Fluticasone? 

Fluticasone works by reducing airway inflammation through inhibition of inflammatory cells and mediators. 

Reference 

1. Fluticasone nasal (Flonase, Veramyst): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing – WebMD [Internet]. Webmd.com. 2024 [cited 2025 Jul 17]. Available from 
2. PubChem. Fluticasone furoate [Internet]. pubchem.ncbi.nlm.nih.gov. Available from 
3. Fluticasone Nasal Dosage Guide with Precautions [Internet]. Drugs.com. Available from 
4. Fluticasone (Nasal Route) Description and Brand Names – Mayo Clinic [Internet]. www.mayoclinic.org. Available from 

Pranathi Chintaluri

Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.