BrandName_389

Category- Allopathy

Medicine Highlights

Uses 1. Treats ear infections caused by bacteria or fungi. 
2. To treat pain, swelling, and irritation inside the ear. 
3. To treat ear infection from spreading to nearby tissues, the middle ear, or becoming more severe.   
Common Side Effects  1. Mild irritation or burning in the ear  
2. Itching or redness around the ear canal 
3. Temporary numbness  
4. Discharge or slight swelling  
5. Rarely, allergic reactions like rash, swelling, or severe itching 
Additional Information 1. If you notice severe pain, persistent irritation, or signs of an allergic reaction, stop using it and contact a doctor. 
2. Avoid touching the dropper tip to your ear to prevent contamination. 
3. Complete the full course even if symptoms improve. 
Storage 1- The medicine should be stored at room temperature 
2- Keep away from sunlight and moisture 
3- Keep away from the reach of children 
How to Take This Medicine The medicine should be taken in the ear as drops  

BrandName Uses 

This oral medication belongs to the class of antibiotics and is used to prevent and treat fungal infection in ear causing:  

  1. Pain 
  2. Redness 
  3. Swelling 
  4. Irritation

Directions for use

  1. Take this medicine exactly as prescribed by your doctor, at the same time each day. 
  2. Do not stop taking this medicine without your doctor’s approval, even if you feel better. 
  3. If you forget to take this medicine, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. 

BrandName side effects 

More Common  

  1. Burning or stinging in the ear  
  2. Itching or irritation in the ear canal 
  3. Temporary numbness or tingling  
  4. Mild redness inside the ear  

Less Common

  1. Allergic reaction (rash, swelling, severe itching) 
  2. Persistent ear pain or increased discomfort 
  3. Hearing changes  
  4. Secondary infection  
  5. Thinning of ear canal skin 

How BrandName works 

This ear drop has 4 active ingredients that provides four actions in one solution. Chloramphenicol fights and kills bacteria causing ear infection, while clotrimazole removes any fungal infection that may be present. Beclomethasone helps reduce swelling, redness, and irritation in the ear, making you feel more comfortable. Lidocaine provides quick pain relief by numbing the ear canal, so you don’t feel discomfort or itching. Together, they not only treat the infection but also reduce pain and inflammation, helping your ear heal faster.   

Safety Measures and Warning 

Allergy/hypersensitivity

If you are allergic to BrandName, you may develop serious allergic reactions like swelling, rash, or itching, so you should avoid these drops. 

Pregnancy and breastfeeding

Some ingredients from this medication may pass into the bloodstream or breast milk in small amounts, so use only if your doctor says it is safe. 

Pregnancy and Breastfeeding

The safety of this cream is not fully known, so use it only after asking your doctor. 

People with Hearing Problems or Ear Surgery History

If you already have hearing issues or have undergone ear surgery, using these drops without advice can cause complications or further damage. 

People with Viral or Tuberculosis Ear Infections

These drops contain a steroid (beclomethasone) which can worsen viral infections (like herpes) or tuberculosis in the ear instead of curing them. 

People with Perforated Eardrum

If you have a hole in your eardrum, these drops can enter deeper into the ear and cause harm, even damaging hearing. 

BrandName Interaction with Other Medicines

Avoid taking BrandName with the following medicines, as it may increase or decrease the desired effect, or in worse cases and it could be fatal: 

BrandName Interaction with Food Product

It is best to avoid fatty and junk foods, alcohol, and too much caffeine as they can weaken your immune system, cause dehydration, and slow healing. Instead, eat a balanced diet with fruits, vegetables, and proteins, and drink plenty of water to help your body recover faster. 

Storage

  1. Store the medicine at room temperature 
  2. Keep away from sunlight and moisture 
  3. Keep out of reach of children 

BrandName Chemical Structure

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Chloramphenicol: 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide 

Beclomethasone: (11b,16b)-9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione  

Clotrimazole: 1-[(2-chlorophenyl)-diphenylmethyl]imidazole 

Lidocaine: 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide 

Intake routine/cycle

Daily dose

Take BrandName exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor. 

Missed Dose

If you forget to take your medicine, take the medication soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage. 

Overdose

Do not use more drops or apply them more often than your doctor recommends. Overusing the drops can cause ear irritation, burning, swelling, temporary numbness, or hearing changes. In rare cases, too much steroid or lidocaine may cause more serious effects. If you notice severe pain, dizziness, ringing in the ears, or unusual symptoms, stop using the drops and contact a doctor immediately. 

BrandName Summary

This ear drop combination is used to treat infected and inflamed ear conditions, especially when bacterial and fungal infections occur along with pain, itching, redness, and swelling. Chloramphenicol helps control bacterial growth, while clotrimazole treats fungal infection of the ear. Beclomethasone reduces inflammation, swelling, and irritation, and lidocaine provides fast relief from ear pain by numbing the affected area. 

The drops help relieve symptoms such as earache, itching, discharge, and discomfort, allowing the ear to heal faster. They should be used exactly as prescribed and only for a short duration. Prolonged or improper use may lead to side effects like irritation, skin thinning inside the ear canal, or masking of infection. These ear drops should not be used if the eardrum is perforated, unless advised by a doctor, and care should be taken especially in children. 

FAQ’s

How does Clotrimazole work? 

Clotrimazole works by damaging the cell membrane of fungi, stopping their growth and reproduction. This helps to clear the fungal infection and relieve symptoms like itching, redness, and irritation. 

How does Betamethasone work? 

Betamethasone works by reducing swelling, redness, and itching on the skin. It does this by blocking chemicals in the body that cause inflammation and irritation. 

Can Beclomethasone be used during pregnancy? 

Beclomethasone should be used during pregnancy only if a doctor advises it. Using too much or for a long time may affect the baby’s growth, so always consult your doctor before applying this medicine when pregnant. 

What are the uses of chloramphenicol? 

Chloramphenicol is an antibiotic that treats infections caused by bacteria, like ear infections, eye infections, or skin infections. It helps stop the bacteria from growing and spreading, so your infection gets better. 

How does chloramphenicol work?

It stops bacteria from making proteins, which they need to grow and multiply. Without these proteins, the bacteria cannot survive or spread, so the infection gets better. 

What mild side effects can chloramphenicol cause? 

You may notice burning, stinging, redness, or itching where the drops are applied. Mild swelling or a feeling of fullness in the ear can also occur. These usually go away on their own. 

Which class of medicine does chloramphenicol belong to? 

Chloramphenicol is in the class of antimicrobials that inhibits protein synthesis and it is also an antibiotic. 

What are the uses of lidocaine? 

Lidocaine is a local anesthetic that numbs an area of the body to reduce pain, itching, or discomfort. 

What mild side effects can lidocaine cause? 

You may notice temporary burning, stinging, or redness where the drops are applied. Some people may feel tingling or numbness in the ear. 

How does lidocaine work? 

Lidocaine works by blocking sodium channels in the nerve cells. Sodium is needed for nerves to send signals, including pain signals, to the brain. By blocking sodium, lidocaine prevents the nerve from sending pain messages, which makes the area numb. 

Reference 

  1. PubChem. Clotrimazole [Internet]. pubchem.ncbi.nlm.nih.gov. Available from 
  2. Drugbank. Clotrimazole [Internet]. Drugbank. 2005. Available from 
  3. Clotrimazole: Antifungal Skin Cream [Internet]. Cleveland Clinic. Available from 
  4. Khatter NJ, Khan MA. Clotrimazole [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2020. Available from 
  5. Truemeds [Internet]. Truemeds.in. 2019 [cited 2025 Aug 21]. Available from 
  6. PubChem. Beclomethasone [Internet]. pubchem.ncbi.nlm.nih.gov. 2021. Available from 
  7. PubChem. Chloramphenicol [Internet]. pubchem.ncbi.nlm.nih.gov. Available from 
  8. PubChem. Lidocaine [Internet]. pubchem.ncbi.nlm.nih.gov. Available from 
  9. Drugbank. Lidocaine [Internet]. go.drugbank.com. 2005. Available from 
  10. Drugbank. Chloramphenicol [Internet]. go.drugbank.com. 2024. Available from 

Authors

  • Pranathi Chintaluri

    Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children's health” which will be published by the end of 2025.

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  • Mahak Phartyal

    Mahak Phartyal completed her bachelor's in pharmacy from Veer Madho Singh Bhandari Uttarakhand Technical University. She previously worked as a Medical Writer at Meril Life Sciences, where she wrote numerous scientific abstracts for conferences such as India Live 2024 and the European Society of Cardiology (ESC). During her college years, she developed a keen research interest and published an article titled “Preliminary Phytochemical Screening, Physicochemical and Fluorescence Analysis of Nyctanthes arbor-tristis and Syzygium cumini Leaves.

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