Category- Allopathy
Medicine Highlights
| Uses | 1. To treat fungal infection in the food pipe (esophageal candidiasis) 2. To treat lung infection caused by fungus (aspergillosis) 3. To treat serious body infections caused by fungus (blastomycosis and histoplasmosis) 4. To treat fungal infection of the fingernails 5. To treat fungal infection of the toenails |
| Common Side Effects | 1. Decreased urine output 2. Dry mouth 3. Fever 4. Increased thirst 5. Irregular heartbeat 6. Loss of appetite 7. Mood changes 8. Muscle pain or cramps 9. Nausea 10. Numbness or tingling in the hands, feet, or lips 11. Seizures 12. Trouble breathing 13. Unusual tiredness or weakness 14. Vomiting |
| Additional Information | BrandName can make you feel dizzy or sleepy. So, avoid driving as it can cause falls, accidents, or severe injuries. |
| Storage | 1- The medicine should be stored at room temperature 2- Keep away from sunlight and moisture 3- Keep away from the reach of children |
| How to Take This Medicine | Swallow this medicine with water |
BrandName Summary
BrandName is an antifungal medication. It kills and stops the growth of fungi by destroying its cell membrane, that is by working on inhibiting the synthesis of ergosterol, which is a crucial compound in the fungal cell membrane, thereby treating your skin infection. Side effects of this medication usually include decreased urine output, dry mouth, fever, increased thirst, irregular heartbeat, loss of appetite, mood changes, and muscle pain or cramps. Alcohol, smoking and grapefruits should be avoided with BrandName, taking more than 400 mg of BrandName per day, as it may cause severe overdosing effects like extreme nausea and vomiting, abdominal pain.
BrandName Uses
BrandName is an oral antifungal medicine belonging to the triazole class of drugs, used to treat fungal infections in various parts of the body including:
- Food pipe (esophageal candidiasis)
- Lung
- Fingernails
- Toenails
BrandName side effects
More Common
- Decreased urine output
- Dry mouth
- Fever
- Increased thirst
- Irregular heartbeat
- Loss of appetite
- Mood changes
- Muscle pain or cramps
- Nausea
- Numbness or tingling in the hands, feet, or lips
- Seizures
- Trouble breathing
- Unusual tiredness or weakness
- Vomiting
Less Common
- Blurred vision
- Chest pain or tightness
- Chills
- Clay-colored stools
- Cloudy urine
- Cold sweats
- Confusion
- Cough
- Dark urine
- Decrease in urine-concentrating ability
- Diarrhea
- Dizziness
- Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- Drowsiness
- Feeling unusually cold
- Headache
- Itching, skin rash
- Light-colored stools
- Mental changes
How BrandName works
BrandName works by blocking a fungal enzyme called cytochrome P450 14α-demethylase, which is responsible for making ergosterol, an essential part of the fungal cell membrane. By stopping the formation of ergosterol, it damages the cell membrane, which leads to the death of the fungus and helps treat the infection.
Directions for use
- If you forget to take the medicine, take it as soon as you remember, unless it’s almost time for the next one, then just skip it.
- BrandName should be taken after meals or as advised by your doctor.
- Follow your doctor’s instructions on the dosage and timing of this medication.
- Swallow BrandName with a glass of water. Do not crush, break, or chew it.
Safety Measures and Warning
Allergies or Hypersensitivity
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines.
Pregnancy
BrandName can harm a baby’s growth if taken during pregnancy, especially affecting the brain and causing tremors, developmental issues, and respiratory depression. Doctors only use it if no safer medicine works
Kidney Disease and Liver Disease
If you have any history of kidney or liver disease tell your doctor as this medicine may worsen your kidney and liver’s condition.
Congestive Heart Failure
If you have a history of heart failure, this medicine should not be used to treat fungal infections of the fingernails or toenails, as it may worsen your heart condition.
Organ Transplant
After organ transplant, you might take medicines which will suppress the release of stomach’s acid by which your stomach might not absorb BrandName properly. Hence it is advised to avoid BrandName in such cases.
BrandName Interaction with Food Product
BrandName has an interaction with grapefruit Juice, so it is better to avoid it. Alcohol and smoking can simultaneously affect the drug’s action, so they may cause severe drowsiness and sedation.
BrandName Interaction with Other Medicines
Avoid taking BrandName with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
BrandName Chemical Structure
IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name
(2R,4S)-rel-1-[2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy-4-[4-(4-[pentyloxy]phenyl)piperazin-1-yl]phenyl]butan-2-ol
Intake routine/cycle
Daily Dose
Take BrandName exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
Missed Dose
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Overdose
Don’t take more than 400 mg of BrandName per day, as it may cause severe overdosing effects like extreme nausea, vomiting, abdominal pain, headache, dizziness or lightheadedness, fatigue or weakness, and skin rash. Consult a doctor if you experience any of these symptoms.
Storage
- Store the medicine at room temperature
- Keep away from sunlight and moisture
- Keep out of reach of children
FAQ’s
Can I take BrandName twice daily?
BrandName is prescribed for onychomycosis (fungal nail infections), systemic fungal infections (like histoplasmosis, blastomycosis), oral or esophageal candidiasis (when severe or resistant to topical treatment) and aspergillosis (lung infection caused by fungus). Whereas it can be taken 2 times in the morning and evening.
What are BrandName capsules tablet use?
It is used for the following infections like onychomycosis (fungal nail infections), systemic fungal infections (like histoplasmosis, blastomycosis), oral or esophageal candidiasis (when severe or resistant to topical treatment), aspergillosis (lung infection caused by fungus).
What are BrandName tablet side effects?
BrandName side effects generally include decreased urine output, dry mouth, fever, increased thirst, irregular heartbeat, loss of appetite, mood changes, muscle pain or cramps, nausea, numbness or tingling in the hands, feet, or lips, seizures.
Reference
- Itraconazole (oral route) [Internet]. Mayo Clinic. 2025 [cited 2025 Jul 14]. Available from
- https://www.facebook.com/Drugscom. Itraconazole Disease Interactions [Internet]. Drugs.com. 2025 [cited 2025 Jul 14]. Available from
- PubChem. Itraconazole [Internet]. Nih.gov. PubChem; 2025 [cited 2025 Jul 14]. Available from
- Kurn H, Wadhwa R. Itraconazole [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2021. Available from
Authors
Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.