Nebivolol 5 mg + Cilnidipine 10 mg

Category- Allopathy

Medicine Highlights

Nebivolol + Cilnidipine Uses

Nebivolol + Cilnidipine is an oral medication belonging to the category of beta-blockers and calcium channel blockers, respectively. It is used for the following indications:

1. High blood pressure (Hypertension) 
2. Prevent sudden spike in blood pressure 
3. Risk of heart attack in patients with high blood pressure. 

Nebivolol + Cilnidipine side effects 

More Common  

1. Dizziness 
2. Swelling in your legs 
3. Slow heartbeats 
4. Tiredness  
5. Headache 

Less Common 

1. A light-headed feeling, like you might pass out 
2. Rapid weight gain 
3. Shortness of breath 
4. Slow or uneven heartbeats 
5. Numbness or cold feeling in your hands and feet 

How Nebivolol + Cilnidipine works 

Nebivolol and cilnidipine are antihypertensive drugs belonging to the beta-blocker and calcium channel blocker classes, respectively. Nebivolol and cilnidipine both relax blood vessels, improve blood flow to arteries and lower blood pressure. Nebivolol works via beta-blockade and nitric oxide release, while cilnidipine blocks calcium channels.

Safety Measures and Warning 

Allergy

Patients with allergies should not take this medicine due to problems like severe low BP that may arise. Consult a doctor before taking the medicine.

Heart Problems

If patients with heart disease like slow heart rate take this medicine, it may cause low blood pressure and heart attack. Recommended to take the medicine only by doctors’ prescription.

Nebivolol + Cilnidipine Interaction with Food Product 

Avoid fatty, salty meals as they reduce nebivolol’s effect. Skip alcohol with nebivolol or cilnidipine, since it can cause dangerous drops in blood pressure.

Nebivolol + Cilnidipine Interaction with Other Medicines  

Avoid taking Nebivolol and cilnidipine with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

Nebivolol + Cilnidipine Chemical Structure

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Nebivolol- (1R)-1-[(2R)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-{[(2R)-2-[(2S)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-hydroxyethyl] amino}ethanol hydrochloride

Cinlidipine- (2-methoxyethyl (2E) -3-phenylprop-2-en-1-yl 2,6-dimethyl-4-(3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate

Intake routine/cycle

Daily dose

Take Nebivolol + Cilnidipine exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

It is not recommended to take more than 40 mg of nebivolol per day or more than 20 mg of cilnidipine per day, as this may cause severe low blood pressure and coma. If symptoms such as fainting or dizziness occur, seek emergency medical attention immediately. 

Storage

1. Store the medicine at room temperature 
2. Keep away from sunlight and moisture 
3. Keep out of reach of children 

Directions for use 

1. Take Nebivolol + Cilnidipine exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking Nebivolol + Cilnidipine without your doctor’s approval, even if you feel better. 
3. If you forget to take Nebivolol + Cilnidipine, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. 

Nebivolol + Cilnidipine Summary 

Nebivolol belongs to a group of drugs known as beta blockers, and cilnidipine is a calcium channel blocker. Both relax blood vessels by improving blood flow and easing the heart’s workload. This helps prevent strokes and heart attacks. Common side effects include rapid weight gain, shortness of breath, slow or uneven heartbeat, and numbness or a cold feeling in your hands and feet. Use the medicine as directed. Do not take more than 40 mg of Nebivolol per day. If it’s taken more than 40 mg per day, it causes a severe fall in BP leading to fainting and unconsciousness; sometimes it may be fatal. Nebivolol and Cilnidipine should be taken with or without food. Consult the physician in case of any abnormality.

FAQ’s

What are the uses of nebivolol tablet?

Nebivolol is commonly used to treat High Blood pressure and heart attacks.

What are the side effects of Nebivolol tablets?

Nebivolol side effects include severe bradycardia, irregular heartbeat, and low BP

Where can I buy nebivolol and cilnidipine online?

You can buy Nebivolol Cilnidipine from SayaCare at an 80% discount. They test every batch of the medicine and publish the test reports on their website, providing you with safe, verified medicine delivered right to your doorstep.

What are cilnidipine 10 mg uses?

It is commonly used to treat high blood pressure and heart attacks.

What is the maximum dose of cilnidipine per day?

The maximum dose of cilnidipine to be taken per day is 20 mg. Taking of excessive doses cause severe fall in BP and causes fainting.

Reference 

1. Drugs.com. Nebivolol Monograph [Internet]. Drugs.com; c2000–2025 [cited 2025 Jun 25]. Available from. 
2. National Center for Biotechnology Information. PubChem Compound Summary for CID 5311057, Cilnidipine [Internet]. Bethesda (MD): National Library of Medicine (US); [cited 2025 Jun 25]. Available from. 
3. National Center for Biotechnology Information. PubChem Compound Summary for CID 71301, Nebivolol [Internet]. Bethesda (MD): National Library of Medicine (US); [cited 2025 Jun 25]. Available from. 
4. Sase N, Kawamura H, Honda A, Takahashi T, Saito Y, Saito K, et al. Cilnidipine: a new generation calcium channel blocker with dual L/N-type channel blocking property for treatment of hypertension. Int J Hypertens [Internet]. 2012 [cited 2025 Jun 25];2012:1–7. Available from. 

Siva Krishna Adithya Bhumireddy

Siva Krishna Adithya Bhumireddy completed Bachelor of Pharmacy from GIET School of Pharmacy affiliated to Andhra University and from his 3rd year of graduation itself he was working as a freelance Medical and Publication writer and having expertise in Systematic reviews and clinical research. With his keen interest and skills in research and documentation practices he also reviewed more than 100 manuscripts from international journals like Elsevier, Springer Nature, Sage Journals and all the manuscripts were indexed and appeared in Pub Med, Scopus and Web of Science databases and received honorary recognition letters and certificates from all of them. Siva Krishna Adithya also published few systematic, narrative reviews and few chapters of international expertise.