Category- Allopathy
Medicine Highlights
| Uses | 1. To treat respiratory tract infections such as bronchitis and pneumonia. 2. To treat sinus infections (sinusitis). 3. To treat urinary tract infections including cystitis and pyelonephritis. 4. To treat skin and soft tissue infections caused by bacteria. 5. To treat ear infections (otitis media). 6. To treat gastrointestinal bacterial infections that cause diarrhea. |
| Common Side Effects | 1. Nausea or vomiting 2. Diarrhea or stomach upset 3. Dizziness or headache 4. Mild rash |
| Additional Information | 1. Take the tablet orally, usually once a day, with or without food, exactly as prescribed by your doctor. 2. Do not skip doses or stop early, even if you feel better. |
| Storage | 1- The medicine should be stored at room temperature 2- Keep away from sunlight and moisture 3- Keep away from the reach of children |
| How to Take This Medicine | This medicine is meant to be taken orally |
Moxifloxacin + Cefixime Uses
Moxifloxacin 400 mg + Cefixime 400 mg tablets are a combination antibiotic medicine used to treat various bacterial infections in the body. It is useful for the following indications:
- Sinus infections (sinusitis), which are infections of the air-filled spaces around the nose.
- Lung infections such as pneumonia and bronchitis, affecting breathing and lung function.
- Skin and soft tissue infections caused by bacteria.
- Infections inside the abdomen (stomach area).
- Urinary tract infections like cystitis and pyelonephritis.
- Ear infections and throat infections like tonsillitis.
Directions for use
- Take this medicine exactly as prescribed by your doctor, at the same time each day.
- Do not stop taking this medicine without your doctor’s approval, even if you feel better.
- If you forget to take this medicine, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose.
Moxifloxacin + Cefixime side effects
More Common
- Nausea or vomiting
- Diarrhea or stomach upset
- Dizziness or headache
- Mild rash
Less Common
- Tendon pain or rupture
- Severe allergic reactions (rash, swelling, difficulty breathing)
- Liver problems (yellowing of skin or eyes, dark urine)
- Irregular heartbeat or palpitations
- Severe diarrhea caused by Clostridium difficile
- Blood disorders like low white blood cells
How Moxifloxacin + Cefixime works
Moxifloxacin + Cefixime is a combination of two antibiotics that work together to fight bacterial infections. Moxifloxacin belongs to the fluoroquinolone group and kills bacteria by stopping them from copying their DNA, which prevents them from growing and spreading. Cefixime belongs to the cephalosporin group and works by stopping bacteria from building their cell walls, which causes the bacteria to die. By using both antibiotics together, this combination can treat a wider range of bacterial infections and help clear the infection faster, especially when a single antibiotic may not be enough.
Safety Measures and Warning
Allergy Warning
If you are allergic, taking the medicine can cause serious reactions like rash, swelling, itching, or difficulty breathing. Always consult your doctor before using it.
History of tendon problems
Moxifloxacin can increase the risk of tendon pain, inflammation, or rupture, especially in older adults. Always check with your doctor first before taking it.
Heart rhythm problems (prolonged QT interval)
The medicine can cause irregular heartbeat or palpitations. Inform your doctor about your condition.
Pregnant or Breastfeeding Women
Safety for the fetus is not fully known. Always talk to your doctor first.
Children and Teenagers
It may affect growing bones and joints in the children. Use only if prescribed by your doctor.
Severe liver or kidney problems
The if you’re suffering with liver or kidney problems, this medicine may stay in your body longer than it should. This can increase the chance of side effects, communicate with your doctor about your condition.
Moxifloxacin + Cefixime Interaction with Food Product
Avoid foods high in calcium, iron, magnesium, and aluminum, such as dairy products (milk, yogurt), nuts, spinach, salmon, and fortified juices, as they may reduce the absorption if taken together with moxifloxacin. Avoid consuming caffeinated food, alcohol and smoking simultaneously as they can alter drugs effect; also, they may cause severe drowsiness and sedation as they act on the brain directly.
Moxifloxacin + Cefixime Interaction with Other Medicines
Avoid taking Moxifloxacin + Cefixime with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Moxifloxacin + Cefixime Chemical Structure
IUPAC (International Union of Pure and Applied Chemistry) / Chemical name
Moxifloxacin: 7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid
Cefixime: 7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(carboxymethoxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Intake routine/cycle
Daily dose
Take Moxifloxacin + Cefixime exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
Missed Dose
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Overdose
Do not take more than 400 mg of moxifloxacin and cefixime as taking too much can increase the risk of serious side effects, such as irregular heartbeat, severe dizziness, nausea, vomiting, or seizures. If you accidentally take more than prescribed, contact your doctor or seek medical help immediately.
Storage
- Store the medicine at room temperature
- Keep away from sunlight and moisture
- Keep out of reach of children
Moxifloxacin + Cefixime Summary
Moxifloxacin + Cefixime tablets are a combination of two antibiotics used to treat a wide range of bacterial infections such as pneumonia, bronchitis, sinus infections, urinary tract infections, skin infections, and abdominal infections. Moxifloxacin (a fluoroquinolone) works by blocking bacterial enzymes needed for DNA copying, stopping their growth and killing them. Cefixime (a cephalosporin) works by damaging the bacterial cell wall, making the bacteria break down and die. Together, they provide a stronger effect against tough or mixed bacterial infections.
Common side effects include nausea, vomiting, diarrhea, stomach pain, headache, or mild rash. Rare but serious effects may include tendon pain or rupture, severe allergic reactions, liver problems, irregular heartbeat, or severe diarrhea. People who are allergic to these antibiotics, have tendon problems, heart rhythm issues, severe liver or kidney disease, children, teenagers, pregnant or breastfeeding women should avoid this combination unless prescribed by a doctor.
FAQ’s
What are the uses of Moxifloxacin tablet?
It is used to treat bacterial infections like pneumonia, bronchitis, sinus infections, skin and soft tissue infections, abdominal infections, and other bacterial infections as prescribed by your doctor.
What are the side effects of Moxifloxacin 400 mg tablets?
Common side effects include nausea, vomiting, diarrhea, headache, and dizziness. Rare but serious side effects may include tendon pain or rupture, severe allergic reactions, liver problems (yellowing of skin or eyes, dark urine), irregular heartbeat, or severe diarrhea caused by Clostridium difficile.
What drug class does Moxifloxacin belong to?
Moxifloxacin belongs to the fluoroquinolone antibiotics class, which work by killing bacteria and treating bacterial infections in the eye.
Who should not take Moxifloxacin?
People who are allergic to Moxifloxacin or other fluoroquinolone antibiotics should not take it, as it can cause serious allergic reactions. It should also be avoided in people with a history of tendon problems related to fluoroquinolones, those with certain heart rhythm disorders (prolonged QT interval), and in children or pregnant women unless specifically prescribed by a doctor.
What are the uses of Cefixime tablet?
Cefixime 400 mg tablet is used to treat bacterial infections such as urinary tract infections (UTIs), throat infections, tonsillitis, ear infections, bronchitis, pneumonia, and certain types of skin infections. It works by killing the bacteria causing the infection.
What are the side effects of Cefixime?
Common side effects of cefixime include diarrhea, stomach pain, nausea, indigestion, gas, and headache. Rare but serious side effects may include severe allergic reactions (rash, itching, swelling, difficulty breathing), yellowing of the skin/eyes (liver problems), or unusual bleeding/bruising (blood problems). If any severe reaction happens, stop the medicine and contact your doctor immediately.
Can Cefixime be taken during pregnancy?
Cefixime is usually considered safe in pregnancy when prescribed by a doctor. However, it should only be taken if the doctor feels the benefits are greater than the risks. Never self-medicate during pregnancy, always consult your doctor before using Cefixime.
Reference
- PubChem. Moxifloxacin [Internet]. pubchem.ncbi.nlm.nih.gov. Available from
- DRUGBANK. Moxifloxacin [Internet]. go.drugbank.com. Available from
- Humma ZE, Patel P. Moxifloxacin [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2024. Available from
- WebMD. Moxifloxacin Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing – WebMD [Internet]. www.webmd.com. Available from
- PubChem. Cefixime [Internet]. Nih.gov. PubChem; 2025 [cited 2025 Sep 4]. Available from
- Cefixime Dosage Guide with Precautions [Internet]. Drugs.com. Available from
Authors
Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.