BrandName_1741

Category- Allopathy

Medicine Highlights

BrandName Summary

BrandName is commonly used to treat indigestion and acid reflux. It helps reduce stomach acid and improves digestion. You might experience mild side effects like headache, gas, or dry mouth. Rarely, it can cause symptoms like dizziness or blurred vision. If you have liver or kidney issues, or if you’re pregnant or breastfeeding, talk to your doctor before starting this medicine. 

Take it exactly as prescribed-same time every day for best results. Avoid grapefruit, alcohol, tobacco, or cranberry, as they may reduce its effectiveness. If you miss a dose, skip it if the next one is near. In case of overdose, watch out for confusion or shakiness and seek medical help. Store it in a cool, dry place away from kids. 

BrandName Uses 

BrandName is an oral medicine belonging to the class of proton pump inhibitor and benzimidazole medicines respectively. It is used for following indications: 

1. Acidity (Gastroesophageal reflux disease) 
2. Indigestion 

How BrandName works 

Pantoprazole reduces stomach acid by blocking the acid pump, like putting a cork in a bottle, and starts working in a few hours. Domperidone helps move food through the stomach faster by making stomach muscles contract. It also helps prevent nausea by blocking signals in the brain that cause vomiting. Together, they reduce acid and improve digestion. This makes eating and digestion more comfortable. 

BrandName side effects

More Common

1. Diarrhea 
2. Stomach pain 
3. Flatulence (gas) 
4. Dry mouth 
5. Dizziness 
6. Headache 

Less Common

1. Loss of balance or muscle control 
2. Swelling of the mouth 
3. Breast milk flowing from the nipple 
4. Blurred vision 
5. Dry mouth 
6. Flushed, dry skin 
7. Fruit-like breath odor 
8. Increased hunger 
9. Increased thirst 
10. Increased urination 
11. Nausea 
12. Somach pain 
13. Sweating 
14. Trouble breathing 

Safety Measures and Warning

1- Allergy/Hypersensitivity

If you have an allergy to BrandName, inform your doctor immediately to avoid or prevent any complications.

2- Kidney dysfunction

If you have pre-existing kidney disease, inform your physician, as they may adjust the dose or decide not to prescribe the medication.

3- Liver dysfunction

This medicine should be avoided in patients with liver disease, as it can be harmful to the liver.

4- Pregnancy

If you are planning to conceive or are pregnant, inform your doctor. BrandName is not usually recommended during pregnancy due to limited information on its safety.

5- Breastfeeding

BrandName is minimally present in breast milk; however, its effects on breast-fed children are not yet fully understood and require further study.

Directions for use

1. Take this medicine exactly as prescribed by your doctor, regularly at the same time each day. 
2. Do not stop taking this medication without your doctor’s approval, even if you feel better. 
3. If you forget to take the medicine, take it as soon as you remember, unless it’s almost time for the next one, then just skip it. 

BrandName Interaction with Other Medicines 

Avoid taking BrandName with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal: 

BrandName Interaction with Food Product

Avoid taking BrandName with grapefruit, grapefruit juice, tobacco, alcohol, or cranberry, as these may alter the effects of the medication. 

BrandName Chemical Structure 

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Domperidone- 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl) propyl]piperidin-4-yl]-1H-benzimidazol-2-one. 

Pantoprazole-5-(difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole 

Storage

1. The medicine should be stored at room temperature  
2. Keep away from sunlight and moisture  
3. Keep away from the reach of children 

Intake routine/cycle 

Daily dose

Take BrandName exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

For humans, there is no specific dose established to determine the exact threshold beyond which BrandName becomes unsafe. However, in cases of overdose, symptoms such as hypoactivity, tremors, difficulty in speaking, disorientation, dizziness and ataxia may occur. 

FAQ’s

1- When should I take domperidone? 

Take this medicine before meals, exactly as your doctor told you. 

2- Can domperidone cause constipation? 

Yes, it has been proven to cause constipation as a side effect. 

3- How much domperidone should I take for lactation? 

To enhance milk secretion, you can take 10 mg of domperidone three times a day. Follow the dosage recommended by your doctor. 

4- Which is better, domperidone or ondansetron? 

In a study conducted among children aged 3 months to 5 years, it was found that ondansetron is more effective than domperidone in preventing vomiting. 

5- Why is domperidone preferred over metoclopramide? 

Metoclopramide is a medicine that can enter the brain and cause side effects, while domperidone acts around the stomach and has fewer side effects. 

6- Is domperidone a painkiller? 

No, domperidone is a medicine that prevents vomiting. 

7- Is domperidone used for loose motion? 

Domperidone increases bowel movements and helps the digested food pass through the anus, so it is not used for loose motion. 

8- How does domperidone increase breast milk? 

Domperidone increases the production of breast milk by increasing the level of milk producing hormone called prolactin 

9- Is domperidone banned in India? 

Domperidone is not banned in India if it is used as a single active ingredient. However, some of its combinations with other medicines are banned in India. 

10- Why is BrandName taken before food? 

BrandName is taken before food because food delays the absorption of the tablet by approximately three to four hours, which can reduce its effectiveness. 

11- Why is BrandName given with antibiotics? 

BrandName is given with antibiotics to treat ulcers caused by a bacterium called Helicobacter pylori (H. pylori). The combination helps eradicate the bacteria and promotes ulcer healing. 

Reference

1. Hanif H, Jaffry H, Jamshed F, Amreek F, Kumar N, Hussain W, Rizwan A. Oral Ondansetron versus Domperidone for Acute Gastroenteritis Associated Vomiting in Young Children. Cureus. 2019 Sep 12;11(9):e5639. doi: 10.7759/cureus.5639. PMID: 31700742; PMCID: PMC6822884.Available from. 
2. The Women’s. Domperidone for increasing breast milk supply. 2019 Feb 26. Available from. 
3. Government of Goa. List of banned FDC drugs in Goa. 2024 Aug. Available from. 
4. Mayo Clinic. Domperidone (Oral route). Available from. 
5. Reddymasu SC, Soykan I, McCallum RW. Domperidone: review of pharmacology and clinical applications in gastroenterology. Am J Gastroenterol. 2007 Sep;102(9):2036-45. doi: 10.1111/j.1572-0241.2007.01255.x. Epub 2007 May 3. PMID: 17488253.Available from. 
6. DrugBank. Domperidone. DrugBank Online. Available from. 
7. NHS. Pantoprazole [Internet]. Available from. 
8. Procter & Gamble. Pantoprazole (Pantoloc) [Internet]. Available from. 
9. Ochoa D, Román M, Cabaleiro T, Saiz-Rodríguez M, Mejía G, Abad-Santos F. Effect of food on the pharmacokinetics of omeprazole, pantoprazole and rabeprazole. BMC Pharmacology and Toxicology. 2020 Dec;21:1-9. Available from. 
10. Vaira D, Zullo A, Vakil N, Gatta L, Ricci C, Perna F, Hassan C, Bernabucci V, Tampieri A, Morini S. Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: a randomized trial. Annals of internal medicine. 2007 Apr 17;146(8):556-63. Available from. 
11. NHS. Pantoprazole: Uses, Side Effects, and Dosage. NHS. [Internet]. 2024 [cited 2024 Dec 9]. Available from. 

Siva Krishna Adithya Bhumireddy

Siva Krishna Adithya Bhumireddy completed Bachelor of Pharmacy from GIET School of Pharmacy affiliated to Andhra University and from his 3rd year of graduation itself he was working as a freelance Medical and Publication writer and having expertise in Systematic reviews and clinical research. With his keen interest and skills in research and documentation practices he also reviewed more than 100 manuscripts from international journals like Elsevier, Springer Nature, Sage Journals and all the manuscripts were indexed and appeared in Pub Med, Scopus and Web of Science databases and received honorary recognition letters and certificates from all of them. Siva Krishna Adithya also published few systematic, narrative reviews and few chapters of international expertise.