Dorzolamide 2%

Category- Allopathy

Medicine Highlights

Dorzolamide Uses  

Dorzolamide 2% eye drops is a carbonic anhydrase inhibitor medicine used to reduce high pressure in the eyes. It is useful for the following indications: 

1. Glaucoma (a condition where high eye pressure can damage the optic nerve) 
2. Ocular hypertension (high eye pressure that could lead to glaucoma) 
3. Prevent vision loss caused by high eye pressure 
4. Lower pressure in the eyes before or after certain eye surgeries (as prescribed by a doctor) 

Directions for use

1. Take this medicine exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking this medicine without your doctor’s approval, even if you feel better. 
3. If you forget to take this medicine, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. 

Dorzolamide side effects 

More Common  

1. Eye burning or stinging when the drops are applied 
2. Blurred vision temporarily after application 
3. Eye redness or irritation 
4. Unusual taste in the mouth (bitter or metallic)  

Less Common

1. Eye swelling or itching 
2. Tearing or watery eyes 
3. Headache 
4. Allergic reactions like rash or swelling around the eyes 

How Dorzolamide works 

Dorzolamide works by reducing the amount of fluid (aqueous humor) in the eyes. In conditions like glaucoma or ocular hypertension, too much fluid builds up leading to increased eye pressure that can damage the optic nerve and affect the vision. Dorzolamide blocks an enzyme called carbonic anhydrase, which helps the eyes to produce this fluid. By lowering the fluid production, it reduces eye pressure, helps protect the optic nerve, and prevents vision loss. 

Safety Measures and Warning 

Allergy Warning

If you are allergic to Dorzolamide or similar sulfonamide medicines, using these drops can cause redness, swelling, itching, or a serious allergic reaction. Inform your doctor in case of any allergic reaction 

Kidney Problems

Those with serious kidney disease should avoid using Dorzolamide drops, because the medicine is removed from the body through the kidneys and could cause harm. Consult your doctor before using this medicine. 

Liver Problems

If you have severe liver problems, these drops may affect your liver function and should only be used under medical supervision. 

Pregnant or Breastfeeding Women

Do not use these drops unless your doctor specifically allows it, as it may affect the fetus growth. 

Infants and Children

Safety in young children has not been fully established, so they should only use it if prescribed by a doctor. 

Dorzolamide Interaction with Food Product

Avoid taking caffeinated food, alcohol and smoking simultaneously as they can cause an increase or decrease in drug action; also, they may cause severe drowsiness and sedation as they act on the brain directly. 

Dorzolamide Interaction with Other Medicines

Avoid taking Dorzolamide with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal: 

Dorzolamide Chemical Structure

IUPAC (International Union of Pure and Applied Chemistry) / Chemical name

Dorzolamide: 4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b] thiopyran-2-sulfonamide; hydrochloride 

Intake routine/cycle

Daily dose

Take Dorzolamide exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor. 

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage. 

Overdose

Do not use more than prescribed dose of dorzolamide. Using too many drops can increase the risk of eye irritation, stinging, redness, or blurred vision. If you experience severe reactions such as swelling around the eyes, eye pain, vision changes, or difficulty breathing, stop using the drops immediately and seek medical attention. 

Storage

1. Store the medicine at room temperature 
2. Keep away from sunlight and moisture 
3. Keep out of reach of children 

Dorzolamide Summary

Dorzolamide 2% eye drops are a carbonic anhydrase inhibitor used to lower high pressure in the eyes. They are commonly prescribed for glaucoma and ocular hypertension to protect the optic nerve and prevent vision loss. The drops work by reducing the amount of fluid (aqueous humor) your eyes produce, which lowers eye pressure. Common side effects include eye stinging or burning, redness, blurred vision, or a bitter taste in the mouth, which are usually mild and temporary.  

People who are allergic to Dorzolamide or sulfonamides, have severe kidney or liver problems, are pregnant or breastfeeding, or are young children should avoid using these drops unless prescribed by a doctor. Wash your hands before use, avoid touching the dropper to your eye, and follow your doctor’s instructions carefully. 

FAQ’s

What are the uses of dorzolamide? 

These drops are used to lower high pressure in the eyes, helping to treat glaucoma or ocular hypertension and protect your eyesight from damage. 

What is the category of dorzolamide? 

Dorzolamide is a carbonic anhydrase inhibitor. It works by reducing the amount of fluid in your eyes, which lowers eye pressure and helps protect your optic nerve and vision. 

What is the price of Dorzolamide 2% eye drops? 

Dorzolamide 2% eye drops price at SayaCare is about 110 rupees, at SayaCare we provide test report with each medicine. Also, at SayaCare we provide you with up to 80% less cost than the market. 

Reference 

1. PubChem. Dorzolamide [Internet]. pubchem.ncbi.nlm.nih.gov. Available from 
2. Dorzolamide [Internet]. go.drugbank.com. Available from 
3. Dorzolamide 2% drops: Uses, Side Effects, Price | Generic | SayaCare [Internet]. Sayacare.in. 2025 [cited 2025 Sep 2]. Available from 

Pranathi Chintaluri

Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.