Category- Suppliments
About Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg
Calcium carbonate 500 mg + alfacalcidol 0.25 mg tablet is an oral supplement. Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg is used to improve calcium levels and support bone health. It is commonly prescribed in calcium deficiency, vitamin D deficiency, osteoporosis, fracture recovery, muscle cramps, and in people with increased calcium needs such as elderly individuals and postmenopausal women.
Calcium carbonate provides a high amount of elemental calcium needed to build and maintain strong bones and teeth. Alfacalcidol is a vitamin D analogue that gets converted into active vitamin D, helping increase calcium absorption from the intestine and maintain proper calcium levels in the blood.
Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg common side effects include constipation, diarrhea, stomach upset, abdominal pain, nausea, vomiting, and bloating. Taking it after food can help reduce stomach discomfort. Avoid taking more than prescribed, as excess calcium or vitamin D can lead to high calcium levels in the blood, which may cause weakness, confusion, or kidney problems.
Medicine Highlights
| Uses | 1. To treat calcium deficiency 2. To prevent and treat osteoporosis (weak and brittle bones) 3. To support bone strength and bone healing 4. To support healthy teeth and muscle function 5. To improve calcium absorption in the body |
| Common Side Effects | 1. Constipation 2. Diarrhea 3. Stomach upset 4. Abdominal pain 5. Nausea 6. Vomiting 7. Bloating 8. Loss of appetite |
| Additional Information | 1. Take at the same time each day to maintain consistent levels in the body. 2. Do not crush, chew, or break the tablet. |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | This medicine should be taken orally with a sip of water. |
Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg Uses
Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg tablet is a calcium and vitamin D analog supplements. Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg is used to treat and relieve symptoms of the following conditions:
- Calcium deficiency (weak bones, muscle cramps, low calcium levels)
- Osteoporosis (weak and brittle bones)
- Bone weakness and fracture healing support
- Vitamin D-related calcium absorption problems
- Support overall bone and teeth health
Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg side effects
More Common
- Nausea
- Stomach discomfort
- Bloating
- Loose stools
Less Common
- Allergic reaction
- Skin rash
- Itching
Directions for use
- Take Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg exactly as prescribed by your doctor, regularly at the same time each day.
- Do not stop taking Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg without your doctor’s approval, even if you feel better.
- If you forget to take the Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg, take it as soon as you remember, unless it’s almost time for the next one, then just skip it.
How Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg works
Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg tablet works by supplying and regulating calcium in the body. Calcium carbonate provides essential calcium required for strong bones and teeth. Alfacalcidol is converted into active vitamin D (calcitriol), which increases calcium absorption from the intestine, reduces calcium loss from the kidneys, and helps maintain proper calcium levels in the blood. Together, they improve calcium levels, reduce bone weakness, and support healthy bones and muscles.
Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg Interaction with Other Medicines
Avoid taking Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg Interaction with Food Product
Avoid taking this medicine with tea, coffee, excess fiber, spinach, and high-phytate foods at the same time, as they may reduce calcium absorption. It is best taken after food with water for better absorption and to reduce stomach upset.
Storage
- The medicine should be stored at room temperature
- Keep away from sunlight and moisture
- Keep away from the reach of children
Intake routine/cycle
Daily dose
Take Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
Missed Dose
If you forget to take your medicine, take the medication soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Recommended Dietary Allowance (RDA)
Calcium
Adults need around 1000 mg per day. Women above 50 years and elderly may need around 1200 mg per day. Children require 700–1300 mg depending on age.
Alfacalcidol
There is no fixed RDA as it is a medicinal form of vitamin D. It is prescribed based on individual needs and medical condition.
Natural Source of Calcium Carbonate 500 mg + Alfacalcidol 0.25 mg
Calcium
Calcium is found in milk, curd, cheese, yogurt, paneer, leafy green vegetables, almonds, sesame seeds, tofu, and fortified foods.
Vitamin D (related to alfacalcidol)
Sunlight exposure, egg yolk, fatty fish, fortified milk, cereals, mushrooms.
FAQ’s
Which foods are rich in calcium?
Calcium-rich foods include milk, curd, cheese, paneer, yogurt, sesame seeds, almonds, ragi, tofu, leafy green vegetables, and fortified cereals.
Which fruits are rich in calcium?
Fruits that contain calcium include oranges, figs, kiwi, papaya, mulberries, and dried apricots. Dried figs are one of the better fruit sources of calcium.
What happens in calcium deficiency?
Calcium deficiency can cause weak bones, muscle cramps, body pain, tingling, weakness, brittle nails, and in severe cases bone thinning or osteoporosis.
What are the uses of alfacalcidol tablets?
Alfacalcidol tablets are used to treat vitamin D deficiency and low calcium levels in the body. They are commonly used in conditions like osteoporosis, rickets, osteomalacia, and in patients with kidney disease where calcium balance is affected.
What are the brand names of alfacalcidol?
Alfacalcidol is available under various brand names such as One-Alpha, Alpha D3, and Alfadol, depending on the manufacturer and region.
What is the role of alfacalcidol in osteoporosis?
In osteoporosis, alfacalcidol helps increase calcium absorption and improves bone strength. It helps slow down bone loss and reduces the risk of fractures by maintaining proper calcium levels in the body.
What is the role of alfacalcidol in renal failure?
In renal failure, the kidneys cannot activate vitamin D properly. Alfacalcidol provides an active form of vitamin D, which helps maintain calcium balance, supports bone health, and prevents bone weakness and related complications.
Reference
- National Institutes of Health. Calcium [Internet]. National Institutes of Health Office of Dietary Supplements. 2024. Available from
- NHS. Calcium – Vitamins and minerals [Internet]. NHS. 2020. Available from
- Alfacalcidol [Internet]. go.drugbank.com. Available from
- PubChem. Alfacalcidol [Internet]. Nih.gov. PubChem; 2025. Available from
- Alfacalcidol capsules (One-Alpha®) [Internet]. Cambridge University Hospitals. 2023. Available from
Authors
Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.