Category- Suppliments
About Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg
Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg e is an oral bone health supplement. Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg is used to prevent and treat calcium deficiency and weak bones. It is commonly given when there is low calcium, vitamin D deficiency, osteoporosis, bone weakness, fracture recovery, muscle cramps, or increased calcium needs in older adults and postmenopausal women. Calcium helps build and maintain strong bones and teeth. Calcitriol is the active form of vitamin D that helps the body absorb calcium better from the intestine and maintain proper calcium levels in the blood. Menaquinone (vitamin K2) helps direct calcium into the bones and supports bone strength.
Common side effects of Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg include constipation, diarrhea, stomach upset, abdominal pain, nausea, vomiting, and bloating. To reduce stomach irritation, it is often better to take it after food. Avoid taking more than prescribed, as too much calcium or vitamin D can be harmful. This combination is widely used for calcium deficiency, osteoporosis, and bone health support.
Medicine Highlights
| Uses | 1. To treat calcium deficiency 2. To prevent and treat osteoporosis (weak and brittle bones) 3. To support bone strength and bone healing 4. To improve calcium absorption in the body 5. To support healthy teeth and muscle function |
| Common Side Effects | 1. Constipation 2. Diarrhea 3. Stomach upset 4. Abdominal pain 5. Nausea 6. Vomiting 7. Bloating 8. Loss of appetite |
| Additional Information | To keep you safe and healthy, use this medicine only with your doctor’s guidance. |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | Take this medication orally with a sip of water. |
Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg Uses
Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg capsule comes under the category of calcium and vitamin supplements. Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg is used to treat and relieve symptoms of the following conditions:
- Calcium deficiency (weak bones, muscle cramps, low calcium levels)
- Osteoporosis (weak and brittle bones)
- Bone weakness and fracture healing support
- Vitamin D-related calcium absorption problems
- Support overall bone and teeth health
Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg side effects
More Common
- Constipation
- Diarrhea
- Stomach upset
- Abdominal pain
- Nausea
- Vomiting
- Bloating
- Loss of appetite
Less Common
- Bloating
- Loss of appetite
- Skin rash
- Itching
- Dizziness
- Allergic reaction
Directions for use
- Take Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg exactly as prescribed by your doctor, regularly at the same time each day.
- Do not stop taking Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg without your doctor’s approval, even if you feel better.
- If you forget to take Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg, take it as soon as you remember, unless it’s almost time for the next one, then just skip it.
How Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg works
Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg works by giving your body the nutrients it needs to build and maintain strong bones. Calcium directly supplies the minerals needed for healthy bones and teeth. Calcitriol is an active form of vitamin D that increases calcium absorption from the intestine and helps maintain proper calcium levels in the blood. Menaquinone (Vitamin K2) helps activate proteins like osteocalcin, which helps move calcium into the bones and supports better bone strength. Together, these ingredients help improve calcium levels, reduce bone loss, and support healthy bones and muscles.
Interaction with Other Medicines
Avoid taking Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Interaction with Food Product
Avoid taking Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg with tea, coffee, excess fiber, spinach, and very high-phytate foods around the same time because they may reduce calcium absorption. It is best taken with water and after food for better absorption and to reduce stomach upset.
Storage
- The medicine should be stored at room temperature
- Keep away from sunlight and moisture
- Keep away from the reach of children
Intake routine/cycle
Daily dose
Take Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
Missed Dose
If you forget to take your medicine, take the medication soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Recommended Dietary Allowance (RDA)
Calcium
The recommended dietary allowance for calcium in adults is about 1000 mg per day. Women above 50 years and older adults may need around 1200 mg per day. Children need around 700–1300 mg depending on age.
Calcitriol
There is no separate daily RDA for calcitriol because it is the active form of vitamin D used as a medicine. For general vitamin D needs, adults usually need around 600 IU daily, and older adults may need around 800 IU daily.
Menaquinone
There is no fixed separate RDA for menaquinone, but the general daily requirement for vitamin K in adults is about 90 mcg for women and 120 mcg for men. Children need lower amounts depending on age.
Natural Source of Calcium 1250 mg + Calcitriol 0.25mcg + Menaquinone 45 mcg
Calcium
Calcium is found in milk, curd, cheese, yogurt, paneer, leafy green vegetables, almonds, sesame seeds, tofu, and fortified foods.
Calcitriol
Calcitriol is not naturally found in foods in the same medicine form, but vitamin D can be obtained from sunlight exposure, egg yolk, fatty fish, fortified milk, fortified cereals, and mushrooms.
Menaquinone
Menaquinone is found in fermented foods such as natto, cheese, curd, egg yolk, chicken, and dairy products.
FAQ’s
What are the uses of calcitriol tablet?
Calcitriol is used for hypocalcemia (low calcium), osteoporosis (brittle bones), osteomalacia (soft bones), hypoparathyroidism (low parathyroid hormone), and latent tetany (muscle twitching).
What are calcitriol side effects?
Common side effects of Calcitriol include hypercalcemia (high blood calcium), loss of appetite, weight loss, nausea, vomiting, headache, drowsiness, weakness, stomach discomfort, urinary tract infection, and rash.
What is the calcitriol dosage for adults?
Adult dose for calcitriol is about 0.25mcg to 0.5mcg.
Which foods are rich in calcium?
Calcium-rich foods include milk, curd, cheese, paneer, yogurt, sesame seeds, almonds, ragi, tofu, leafy green vegetables, and fortified cereals.
Which fruits are rich in calcium?
Fruits that contain calcium include oranges, figs, kiwi, papaya, mulberries, and dried apricots. Dried figs are one of the better fruit sources of calcium.
What happens in calcium deficiency?
Calcium deficiency can cause weak bones, muscle cramps, body pain, tingling, weakness, brittle nails, and in severe cases bone thinning or osteoporosis.
What are the side effects of menaquinone?
Menaquinone (vitamin K2) usually has very few side effects when taken in normal doses. Rarely, it may cause stomach upset, nausea, diarrhea, or loss of appetite. The most important caution is that it can interact with blood thinners like warfarin.
What happens in menaquinone deficiency?
Menaquinone (vitamin K2) deficiency can cause easy bruising, bleeding, slow blood clotting, weak bones, and increased risk of bone thinning. Severe vitamin K deficiency is rare in adults, but it can happen in people with poor absorption, long-term antibiotics, liver problems, or poor diet.
What is the daily dose of menaquinone?
There is no separate official RDA for menaquinone (vitamin K2). The general daily vitamin K need in adults is about 90 mcg for women and 120 mcg for men. In supplements, menaquinone-7 (MK-7) is commonly used in doses like 45–100 mcg daily, depending on the product and doctor’s advice.
Reference
- Beulens JWJ, Booth SL, van den Heuvel EGHM, Stoecklin E, Baka A, Vermeer C. The role of menaquinones (vitamin K2) in human health. British Journal of Nutrition. 2013 Apr 16;110(8):1357–68.
- WebMD. Vitamin K: Uses, Side Effects, Interactions, Dosage, and Warning [Internet]. Webmd.com. 2019. Available from
- National Institutes of Health. Calcium [Internet]. National Institutes of Health Office of Dietary Supplements. 2024. Available from
- NHS. Calcium – Vitamins and minerals [Internet]. NHS. 2020. Available from
- Calcitriol Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing – WebMD [Internet]. www.webmd.com. Available from
- Calcijex, Rocaltrol (calcitriol) dosing, indications, interactions, adverse effects, and more [Internet]. reference.medscape.com. Available from
- Lung BE, Mowery ML, Komatsu DEE. Calcitriol [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2021. Available from
Authors
Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.