Voriconazole 200 mg

Category- Allopathy

Medicine Highlights

Voriconazole Uses

Voriconazole 200 mg is an antifungal medicine used to treat serious fungal infections in the body caused by fungi and yeast. It is useful for the following: 

1. Serious fungal infections affecting the lungs, blood, and other organs 
2. Fungal infections of the mouth and food pipe 
3. Severe fungal infections that occur in people with weak immune systems or other medical conditions    

Voriconazole side effects 

More Common  

1. Nausea 
2. Vomiting 
3. Headache 
4. Stomach pain 
5. Diarrhea 
6. Changes in vision      

Less Common 

1. Skin rash or itching 
2. Yellowing of the skin or eyes (liver problems) 
3. Severe allergic reactions such as swelling or difficulty breathing 
4. Severe skin reactions to sunlight      

How Voriconazole works 

Voriconazole works by stopping the growth of fungi. It blocks the production of ergosterol, an essential component of the fungal cell membrane. Without ergosterol, the fungal cell membrane becomes weak and damaged, which prevents the fungus from growing and multiplying, helping the body clear the infection.

Safety Measures and Warning 

Allergy or Hypersensitivity

If you have experienced a skin rash, itching, swelling, or allergic reaction after taking this medicine or similar antifungal medicines should avoid using this medicine and inform their doctor.

Liver disease

People with liver problems or a history of liver disease should avoid using this medicine, as it may worsen liver function.

Pregnancy

Pregnant women should avoid using this medicine unless it is clearly recommended by a doctor.

Breastfeeding

Breastfeeding mothers should consult a doctor before using this medicine, as the medicine may pass into breast milk and affect the baby.

Voriconazole Interaction with Food Product 

Voriconazole tablets should usually be taken on an empty stomach, at least 1 hour before or 1 hour after food, as food may reduce its absorption. Avoid alcohol during treatment, as it may increase the risk of liver-related side effects. If you have any concerns about diet while taking this medicine, consult your doctor. 

Voriconazole Interaction with Other Medicines  

Avoid taking Voriconazole with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

Voriconazole Chemical Structure

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Voriconazole: (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol 

Intake routine/cycle

Daily dose

Take Voriconazole exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

 It is not recommended to take more than 350 mg of Voriconazole per day, as it may cause severe overdose symptoms like nausea, vomiting, headache, tremors, restlessness, and rapid heartbeat.

Storage

1. Store the medicine at room temperature. 
2. Keep away from sunlight and moisture. 
3. Keep out of reach of children. 

Directions for use 

1. Take this medicine exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking this medicine without your doctor’s approval, even if you feel better. 
3. If you forget to take this medicine, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose.  

Voriconazole Summary 

Voriconazole 200 mg is an antifungal medicine used to treat serious fungal infections affecting the lungs, blood, mouth, food pipe, and other organs, especially in people with weak immune systems. It belongs to the triazole class of antifungal drugs and works by stopping the growth of fungi in the body. The medicine is usually taken on an empty stomach as advised by a doctor for better absorption. Common side effects may include nausea, vomiting, headache, stomach pain, diarrhea, and vision changes, while rare effects may include skin rash or liver problems.  

It should be used with caution in people with liver disease, heart rhythm problems, kidney disorders, or during pregnancy and breastfeeding, and medical advice is important before use. Taking more than 350 mg may lead to overdose, which can increase the risk of severe side effects, so it should always be taken only in the prescribed dose.

FAQ’s

What are the uses of voriconazole? 

Voriconazole is used to treat serious fungal infections affecting the lungs, blood, mouth, food pipe, and other organs, especially in people with weak immune systems. 

What is the drug class of voriconazole? 

Voriconazole belongs to the class of antifungal medicines, specifically the triazole antifungal group. 

Can voriconazole be used in renal failure? 

Voriconazole tablets can usually be used in people with renal (kidney) problems, but it should be taken only under medical supervision, as the doctor may adjust the treatment based on the patient’s condition. 

What is the price of voriconazole 200 mg tablets? 

Voriconazole 200 mg tablets price at SayaCare is about 420 rupees, at SayaCare we provide test reports with each medicine. Also, at SayaCare we provide you medicines with up to 80% less cost than the market. 

Reference 

1. Voriconazole (oral route) [Internet]. Mayo Clinic. 2024. Available from 
2. PubChem. Voriconazole [Internet]. Nih.gov. PubChem; 2019. Available from 
3. DRUGBANK. Voriconazole [Internet]. go.drugbank.com. Available from 

Pranathi Chintaluri

Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.