Category- Allopathy
Medicine Highlights
| Uses | 1. To treat muscle pain and spasms 2. To treat back pain 3. To treat neck pain 4. To treat joint pain |
| Common Side Effects | 1. Nausea 2. Stomach pain 3. Indigestion 4. Dizziness 5. Drowsiness 6. Loose motions (diarrhea) 7. Weakness or tiredness |
| Additional Information | 1. Take it exactly as prescribed by your doctor. 2. Avoid smoking, as it can reduce the medicine’s effect. 3. Inform your doctor if you have heart, liver, or kidney problems. |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | Take this medication orally with a sip of water. |
Aceclofenac 100 mg + Paracetamol 325 mg + Chorzoxazone 250 mg Uses
This is a combination medicine and is used to treat in the following conditions:
- Muscle pain and spams
- Back pain
- Neck pain
- Joint pain
Aceclofenac + Paracetamol + Chorzoxazone side effects
More Common
- Nausea
- Stomach pain
- Indigestion
- Dizziness
- Drowsiness
- Loose motions (diarrhea)
- Weakness or tiredness
Less Common
- Skin rash
- Vomiting
- Dry mouth
- Constipation
- Blurred vision
- Low blood pressure
- Allergic reaction (rare)
How Aceclofenac + Paracetamol + Chorzoxazone works
Aceclofenac + Paracetamol + Chlorzoxazone works by reducing pain, swelling, and muscle tightness. Aceclofenac helps lower the chemicals in the body that cause pain and inflammation. Paracetamol helps reduce pain and can also lower fever if present. Chlorzoxazone acts on the nervous system to relax the muscles and reduce muscle spasms. Together, this combination helps relieve painful muscle conditions more effectively.
Safety Measures and Warning
Allergy or Hypersensitivity
If you are allergic to this medicine or any ingredients in this medicine, consult your doctor before taking it because it can cause serious allergic reactions like rash, swelling, or trouble breathing.
Kidney problems
If you have kidney disease, consult your doctor before taking this medicine because it can worsen kidney function and cause the medicine to build up in the body.
Liver problems
If you have liver disease, consult your doctor before taking this medicine because it can increase the risk of side effects and may worsen liver problems.
Stomach ulcer or stomach bleeding
If you have a stomach ulcer, acidity, or bleeding in the stomach, consult your doctor before taking this medicine because it can increase stomach irritation and raise the risk of bleeding.
History of blood clots
If you have a history of blood clots, stroke, deep vein thrombosis (DVT), or clotting problems, consult your doctor before taking this medicine because it can increase the risk of dangerous blood clots.
Heart disease
If you have heart disease or high blood pressure, consult your doctor before taking this medicine because it can cause fluid retention and may worsen heart problems.
Pregnancy
If you are pregnant, consult your doctor before taking this medicine because it may affect the baby, especially in the later months of pregnancy.
Breastfeeding
If you are breastfeeding, consult your doctor before taking this medicine because small amounts may pass into breast milk and may affect the baby.
Aceclofenac + Paracetamol + Chorzoxazone Interaction with Food Product
This medicine can be taken after food to help reduce stomach upset. It is best to avoid or limit alcohol while taking this medicine because it can increase drowsiness and may raise the risk of stomach irritation or liver problems. Very heavy or oily meals may also cause more stomach discomfort in some people.
Aceclofenac + Paracetamol + Chorzoxazone Interaction with Other Medicines
Avoid taking Aceclofenac + Paracetamol + Chorzoxazone with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Aceclofenac + Paracetamol + Chorzoxazone Chemical Structure
IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name
Aceclofenac: 2-[2-[2-[(2,6-dichlorophenyl)amino]phenyl]acetyl]oxyacetic acid
Paracetamol – N-acetyl-para-aminophenol (APAP), acetaminophen
Chorzoxazone: 5-chloro-3H-1,3-benzoxazol-2-one
Intake routine/cycle
Daily dose
Take Aceclofenac + Paracetamol + Chorzoxazone exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
Missed Dose
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Overdose
it is not recommended to take this combination more than the prescribed dose by doctor, as it may cause severe overdose symptoms like nausea, vomiting, headache, tremors, restlessness, and rapid heartbeat.
Storage
- Store the medicine at room temperature.
- Keep away from sunlight and moisture.
- Keep out of reach of children.
Directions for use
- Take this medicine exactly as prescribed by your doctor, at the same time each day.
- Do not stop taking this medicine without your doctor’s approval, even if you feel better.
- If you forget to take this medicine, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose.
Aceclofenac + Paracetamol + Chorzoxazone Summary
Aceclofenac 100 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg is a combination medicine used to relieve pain, swelling, and muscle spasm in conditions such as muscle pain, back pain, neck pain, joint pain, sprains, and strains. Aceclofenac helps reduce pain and inflammation, Paracetamol helps lower pain and fever, and Chlorzoxazone works by relaxing the muscles. This medicine should be taken exactly as advised by the doctor, preferably after food to reduce stomach discomfort.
Common side effects may include nausea, stomach pain, acidity, dizziness, drowsiness, or weakness. Avoid alcohol while taking this medicine, as it may increase the risk of side effects like drowsiness or liver problems. Use it carefully and do not take it for a long time without medical advice.
FAQ’s
Can paracetamol make you sleepy?
Yes, paracetamol is made up of acetaminophen, which is responsible for causing drowsiness, a common side effect.
Can paracetamol cure colds?
No, paracetamol is used to treat pain and fever.
How many paracetamols can we take in a day?
An adult can take up to 2 tablets of 500 mg with a 6-hour gap, up to four times a day. Children aged 10-15 years can take 1 tablet four times a day, with a gap of 4-6 hours between doses.
Can paracetamol delay periods?
No, there is no side effect of paracetamol that affects the pattern of periods. A delay in periods can occur due to many reasons.
How much paracetamol can I take when pregnant?
You can take 500 mg of paracetamol up to four times a day. Paracetamol does not cross the placenta and is not known to cause harm to your fetus.
Can paracetamol be used for headaches?
Yes, paracetamol is used to treat headaches.
What are the side effects of Aceclofenac?
Common side effects include stomach pain, acidity, nausea, dizziness, headache, and rash. Rarely, it may cause liver or kidney problems, high blood pressure, or gastric bleeding with long-term use.
What is the usual dose of Aceclofenac per day?
The typical adult dose is 100 mg twice a day (morning and evening), preferably after meals. Do not exceed 200 mg per day unless advised by your doctor.
How does Aceclofenac work (mode of action)?
Aceclofenac works by blocking COX enzymes, especially COX-2, which produce prostaglandins chemicals that cause pain and inflammation. By lowering prostaglandin levels, it helps reduce pain, swelling, and stiffness.
What are Aceclofenac 100 mg + Thiocolchicoside 4 mg tablet uses?
This medicine is given to reduce pain, swelling, and muscle stiffness. It helps you feel better if you have back pain, joint pain, or muscle spasms.
How much does the Aceclofenac 100 mg + Thiocolchicoside 4 mg tablet cost in India?
In India, this medicine costs roughly ₹50 to ₹60 for a strip of 10 tablets, depending on the brand and pharmacy.
What are the uses of Chlorzoxazone tablets?
Chlorzoxazone tablets are used to relax muscles and relieve pain caused by muscle spasms, muscle stiffness, back pain, neck pain, sprains, and other painful muscle conditions.
What are the side effects of Chlorzoxazone?
Common side effects of Chlorzoxazone may include drowsiness, dizziness, weakness, stomach upset, nausea, and tiredness. In rare cases, it may also cause allergic reactions or liver-related problems.
Reference
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- PubChem. Aceclofenac [Internet]. pubchem.ncbi.nlm.nih.gov. Available from
- Aceclofenac [Internet]. go.drugbank.com. Available from
- Aceclofenac 100 mg Film-coated Tablets – Summary of Product Characteristics (SmPC) – (emc) | 2389 [Internet]. Medicines.org.uk. 2023 [cited 2025 Jul 25]. Available from
- Medicover Hospitals. Aceclofenac | Side Effects | Dosage | Precautions | Medicine [Internet]. Medicoverhospitals.in. 2021. Available from
Authors
Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.