Category- Allopathy
Medicine Highlights
| Uses | 1. To treat seasonal allergies or allergic rhinitis (running nose, sneezing and itching) 2. To treat swelling in nose (nasal polyps) |
| Common Side Effects | 1. Burning or stinging feeling right after applying 2. Itching or dryness at the site 3. Redness or irritation of the skin 4. Tingling or pain where applied |
| Additional Information | 1. Inform your doctor if you have recent nasal surgery, injury, or infections 2. Do not share the spray with others. |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | Spray the contents into each nostril by placing the nozzle inside the nose. |
Mometasone Uses
Mometasone 0.05% is a nasal spray belonging to the class of steroids and used for various types of immune-related allergic rhinitis/seasonal allergies and nasal polyps
Mometasone side effects
More Common
- Burning or stinging feeling right after applying
- Itching or dryness at the site
- Redness or irritation of the skin
- Tingling or pain where applied
Less Common
- Burning
- Itching
- Thinning of the skin with easy bruising, especially when used on the face or where the skin folds together
- Acne or pimples
- Burning, itching, and pain in hairy areas, or pus at the root of the hair
- Dry mouth
- Loss of elasticity
- Loss of normal skin markings
- Raised, dark red, and wart-like spots on the skin, especially when used on the face
- Shininess
How Mometasone works
Mometasone works by binding to glucocorticoid receptors in skin cells and changing the gene function to decrease the production of inflammatory proteins. This results in reduced swelling, redness, and itching in the affected skin
Safety Measures and Warning
Pregnancy
It is considered safe to use during pregnancy.
Breastfeeding
It is safe to use while breastfeeding.
Broken or Damaged Skin
Avoid applying it to open wounds, ulcers, or severely damaged skin because it can increase systemic absorption and can cause toxicity
Allergy or Hypersensitivity
If you have previously had an allergy to this medicine, inform your doctor.
Mometasone Interaction with Food Product
Mometasone does not interact with food products, as it can be applied on the skin only. So, it is safe to use without any fear of food interactions.
Mometasone Interaction with Other Medicines
Avoid taking mometasone 0.05 % with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Mometasone Chemical Structure
IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name
[(8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate
Intake routine/cycle
Daily dose
Take mometasone exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
Missed Dose
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Overdose
Apply mometasone spray as per doctor’s instructions; do not consume orally. If ingested orally by mistake, overdose symptoms may occur and include nausea, irritation, and vomiting; excessive skin application causes marks on skin and burning sensations.
Storage
- Store the medicine at room temperature.
- Keep away from sunlight and moisture.
- Keep out of reach of children.
Directions for use
- Shake the bottle gently and spray once into each nostril as directed.
- Breathe gently in through your nose while spraying.
- Wipe the nozzle clean after use and replace the cap.
Mometasone Summary
Mometasone nasal spray (0.05%) is a corticosteroid used for allergic rhinitis and nasal polyps. It works by reducing inflammation in the nasal passages through suppression of immune chemicals. Relief usually begins within a few days, but maximum benefit may take up to two weeks with regular use. Common side effects include nosebleeds, nasal irritation, sore throat, and headache. Since it is applied locally in the nose, there are no food interactions, but patients with recent nasal surgery, untreated nasal infections, or allergies to corticosteroids should avoid it. Children should use it only under strict medical guidance, as long-term use may affect growth. Overdose is uncommon, but using multiple sprays far beyond the prescribed dose or applying it for extended periods without supervision can increase the risk of systemic steroid effects
FAQ’s
What does mometasone do to the nose?
Mometasone nasal spray reduces inflammation in the nose by binding to glucocorticoid receptors, which suppresses the release of inflammatory mediators and decreases swelling, mucus production, and irritation in the nasal passages. This leads to relief from congestion, sneezing, and runny nose.
What are the side effects of mometasone spray?
The most common side effects of mometasone nasal spray are mild and include nosebleeds, nasal irritation, sore throat, headache, and an unpleasant taste or smell. Rare but serious effects can include fungal infections (thrush), vision changes, or systemic steroid effects if used in very high doses or for prolonged periods.
What are the drug interactions of mometasone?
Mometasone nasal spray has relatively few drug interactions, but caution is advised when used with other corticosteroids or medicines that affect immune function.
Is mometasone a steroid?
Yes, mometasone is a super-potent topical corticosteroid (steroid medicine) used on the skin to reduce inflammation, redness, and itching in conditions like psoriasis and eczema.
Reference
- Elsevier. Mometasone furoate [Internet]. ScienceDirect Topics: Nursing and Health Professions. Available from.
- Vaidya S, Ziegler D, Tanase AM, Malmqvist U, Kanniess F, Hederer B, Hosoe M. Pharmacokinetics of mometasone furoate delivered via two dry powder inhalers. Pulm Pharmacol Ther. Available from.
- PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 441336, Mometasone Furoate; [cited 2026 Feb. 18]. Available from.
- Mayo Clinic. Mometasone (topical application route) [Internet]. Mayo Clinic; 2026 Feb 1 [cited 2026 Feb 18]. Available from.
- Drugs.com. Mometasone topical [Internet]. Drugs.com; 2026 [cited 2026 Feb 18]. Available from.
Authors
Siva Krishna Adithya Bhumireddy completed a Bachelor of Pharmacy from GIET School of Pharmacy, affiliated with Andhra University, and from his 3rd year of graduation, he was working as a freelance medical and publication writer. Having expertise in systematic reviews and clinical research. With his keen interest and skills in research and documentation practices, he also reviewed more than 150 manuscripts from international journals like Elsevier, Springer Nature, and Sage Journals, and all the manuscripts were indexed and appeared in PubMed, Scopus, and Web of Science databases, and he received honorary recognition letters and certificates from all of them. Siva Krishna Adithya also published a few systematic, narrative reviews and a few chapters of international expertise.