Category- Allopathy
Medicine Highlights
| Uses | 1. To treat heart attacks/failure 2. To control very fast heartbeats (tachycardia) |
| Common Side Effects | 1. Slow or irregular heartbeats 2. High blood pressure 3. Your eyes may be more sensitive to light. |
| Additional Information | 1. Take medicine every day at the same time to maintain the drug well in the blood. 2. Do not stop the medicine usage suddenly |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | Take this medicine orally with a sip of water. |
Ivabradine Uses
Ivabradine 5 mg is an oral medicine belonging to the category of antianginal drugs and is used for the following indications:
- Heart failures or attacks
- Rapid heartbeats (tachycardia)
Ivabradine side effects
More Common
- Slow or irregular heartbeats;
- High blood pressure; or
- Your eyes may be more sensitive to light.
Less Common
- Fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out)
- Very slow heartbeats
- Severe headache, blurred vision, pounding in your neck or ears
- Racing heartbeats with dizziness, tiredness, or a lack of energy
- Chest tightness
- Shortness of breath is worse than usual.
How Ivabradine works
Ivabradine slows the heart rate by acting on the heart’s natural pacemaker. This allows the heart to rest longer between beats, improves blood flow, and reduces strain. It is especially helpful in conditions like angina and heart failure, where a slower heart rate eases chest pain and supports heart function.
Safety Measures and Warning
Pregnancy
Pregnant women are not recommended to take ivabradine due to a lack of safety studies, and it should only be used in emergencies under a doctor’s guidance.
Breastfeeding
Ivabradine passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should stop breastfeeding or stop taking Ivabradine.
Low Blood Pressure
Ivabradine can cause severe reduction in heartbeats, so people with low blood pressure are not recommended to use it. People get symptoms such as dizziness or faint if they use it.
Heart Problems
People with severe or worsening heart failure should not take ivabradine, as it may seriously reduce the heart rate, which may lead to fatal consequences.
Ivabradine Interaction with Food Product
The use of drinks that contain alcohol raises your risk of low blood pressure from Ivabradine. If you drink alcohol, talk to your doctor. You may need to have your blood pressure monitored while you take this drug.
Ivabradine Interaction with Other Medicines
Avoid taking Ivabradine 5 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Ivabradine Chemical Structure
IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name
3-[(7S)-5,6,7,8-tetrahydro-7-{[(3,4-dimethoxyphenyl)methyl]amino}imidazo[1,2-a]pyridin-2-ylmethyl]-5,6-dimethylpyridin-2(1H)-one
Intake routine/cycle
Daily dose
Take Ivabradine exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
Missed Dose
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Overdose
It is not recommended to take more than 30 mg of Ivabradine per day, as it may cause severe overdosing effects like extreme drowsiness, confusion, unconsciousness, sweating, double vision, low blood pressure, and slurred speech. Immediately seek medical attention and meet the doctor if necessary.
Storage
- Store the medicine at room temperature
- Keep away from sunlight and moisture
- Keep out of reach of children
Directions for use
- Take Ivabradine exactly as prescribed by your doctor, at the same time each day.
- Do not stop taking Ivabradine without your doctor’s approval, even if you feel better.
- If you forget to take Ivabradine, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose.
Ivabradine Summary
Ivabradine belongs to the selective sinus node inhibitors that help slow down a fast heartbeat without making the heart weaker. It’s used mainly in people with heart failure or a very fast heartbeat when other treatments don’t work well. Ivabradine works by blocking a signal in the heart’s muscles, helping the heart to beat slower and more steadily. Common side effects include slow heartbeat, dizziness, flashing lights, or low blood pressure. It should not be taken by people with low heart rates, serious heart rhythm problems, liver disease, or during pregnancy. It’s best taken with food and should not be mixed with grapefruit juice. Ivabradine overdoses above 40–100 mg can cause dangerous slow heart rate, especially in older adults or people with kidney, liver, or heart conduction problems.
FAQ’s
What is the drug class of ivabradine?
Ivabradine is used for indications like heart attacks and rapid heartbeat. belongs to the class of selective sinus node inhibitors.
What are the side effects of Ivabradine tablets?
Common side effects of ivabradine include slow heartbeat, dizziness, flashing lights, or high blood pressure.
What are the recommendations for the use of ivabradine during pregnancy?
Pregnant women are not recommended to take ivabradine, as there are no studies supporting its safety in pregnancy. So, get a recommendation from a doctor in case of emergency before using it.
What is Ivabradine highest dose?
It is recommended to take 7.5 mg of ivabradine daily in two doses. so that makes it a patient can take up to 15 mg per day
Reference
- Poppen A. Ivabradine (Corlanor): Uses, Side Effects, Interactions, Pictures, Warnings and Dosing [Internet]. WebMD. 2024 Nov 29 [cited 2025 Jul 12]. Available from.
- Cerner Multum. Ivabradine: Uses, Side Effects, Warnings and Interactions [Internet]. Drugs.com. . 2025 Mar 13 [cited 2025 Jul 12]. Available from.
- Reed M, Patel P, Nicolas D. Ivabradine [Internet]. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2025 Feb 15 [cited 2025 Jul 12]. Available from.
- Kim S. Ivabradine: Chemical Structure, Synonyms, and Pharmacology [Internet]. PubChem. 2025 Jul 5 [cited 2025 Jul 12]. Available from.
- Merative, Micromedex®. Ivabradine (oral route): Description, Dosage, and Precautions [Internet]. Mayo Clinic. 2025 Jul 1 [cited 2025 Jul 12]. Available from.
Authors
Siva Krishna Adithya Bhumireddy completed Bachelor of Pharmacy from GIET School of Pharmacy affiliated to Andhra University and from his 3rd year of graduation itself he was working as a freelance Medical and Publication writer and having expertise in Systematic reviews and clinical research. With his keen interest and skills in research and documentation practices he also reviewed more than 100 manuscripts from international journals like Elsevier, Springer Nature, Sage Journals and all the manuscripts were indexed and appeared in Pub Med, Scopus and Web of Science databases and received honorary recognition letters and certificates from all of them. Siva Krishna Adithya also published few systematic, narrative reviews and few chapters of international expertise.