Ticagrelor 60 mg

Category- Allopathy

Medicine Highlights

Ticagrelor Uses

Ticagrelor 60 mg is an oral medicine belonging to the category of selective serotonin receptor agonists used to treat a severe type of constipation with no known cause (chronic idiopathic).

Ticagrelor side effects 

More Common  

1. Back pain 
2. Bleeding gums 
3. Blurred vision 
4. Chest pain, tightness, or discomfort 
5. Confusion 
6. Cough 
7. Coughing up blood 
8. Difficult or trouble breathing 
9. Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position 
10. Fast, slow, or irregular heartbeat 
11. Headache 
12. Increased menstrual flow or vaginal bleeding 
13. Lightheadedness, dizziness, or fainting 
14. Loss of consciousness 
15. Nausea or vomiting 
16. Nervousness 
17. Nosebleeds 
18. Paralysis 
19. Pounding in the ears 
20. Prolonged bleeding from cuts 
21. Red or black, tarry stools 
22. Red or dark brown urine 
23. Sweating 
24. Unusual bleeding or bruising 
25. Unusual tiredness or weakness 

Less Common 

1. Change in mental status 
2. Difficulty in speaking 
3. Fever 
4. Pale skin 
5. Pinpoint red spots on the skin 
6. Seizures 
7. Yellow eyes or skin 

How Ticagrelor works 

In heart disease, platelets can clump and form clots that block blood flow, leading to heart wall damage. Ticagrelor steps in like a shield, blocking the P2Y12 receptor on platelets so they can’t stick together and cause trouble. By keeping blood flowing smoothly all over the body, it lowers the chance of clot formation in people with acute coronary syndrome or past heart attacks. 

Safety Measures and Warning 

Pregnancy

Safety studies of ticagrelor are limited with increased risk of bleeding in pregnant women. So, doctors often recommend switching to a safer option.

Breastfeeding

Ticagrelor isn’t usually advised while breastfeeding due to unknown effects on the baby. Always talk to your doctor before using it.

Kidney and Liver Problems

Ticagrelor is safe to use in kidney or liver disease.

Ticagrelor Interaction with Food Product 

Avoid consuming alcohol and smoking simultaneously, as it may affect the drug’s action and show effects like falling blood pressure, leading to severe drowsiness, sedation, and coma in severe cases.

Ticagrelor Interaction with Other Medicines  

Avoid taking Ticagrelor 60 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

Ticagrelor Chemical Structure

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

(1S,2S,3R,5S) -3-[7-[(1R,2S)-2-(3,4-difluorophenyl) cyclopropyl amino] -5-(propyl Thio) -3H-[1,2,3] triazolo[4,5-d] pyrimidin-3-yl] -5-(2-hydroxyethoxy) cyclopentane -1,2-diol.

Intake routine/cycle

Daily dose

Take Ticagrelor exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

It is not recommended to take more than 180 mg of Ticagrelor per day, as it may cause severe overdosing effects like confusion, unconsciousness, sweating, double vision, low blood pressure, and slurred speech. Immediately seek medical attention and meet the doctor if you experience overdose symptoms.

Storage

1. Store the medicine at room temperature 
2. Keep away from sunlight and moisture 
3. Keep out of reach of children 

Directions for use 

1. Take Ticagrelor exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking Ticagrelor without your doctor’s approval, even if you feel better. 
3. If you forget to take Ticagrelor, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. 

Ticagrelor Summary 

Ticagrelor is a prescription medicine used to treat chronic constipation when other remedies like fiber or laxatives haven’t worked. It works by gently stimulating a specific receptor in the gut (called 5-HT4), helping the intestines move more naturally and making bowel movements easier. Common side effects include nausea, stomach pain, diarrhea, headache, and feeling tired. People with serious gut problems like blockages, Crohn’s disease, or a tear in the intestine should avoid it. It’s generally safe with food and doesn’t have major drug interactions but always check with your doctor before combining it with other medicines. Think of it as a gentle nudge to your digestive system when it’s being stubborn.

FAQ’s

What are the uses of ticagrelor 90 mg tablets?

Ticagrelor 90 mg tablets are used to prevent heart attacks, strokes, and blood clots in people with acute coronary syndrome or a history of heart attack. They help keep platelets from sticking together, reducing the risk of dangerous clots.

What are the side effects of ticagrelor tablets?

Common side effects of ticagrelor include bleeding, shortness of breath, headache, and slow heart rate. Rarely, it may cause dizziness, nausea, or increased uric acid levels.

What is the drug class of ticagrelor tablets?

Ticagrelor belongs to the drug class called antiplatelet agents, specifically a P2Y12 receptor antagonist, which helps prevent blood clots by stopping platelets from sticking together.

What are the contraindications of ticagrelor tablets?

Ticagrelor is contraindicated in patients with active bleeding, a history of intracranial hemorrhage, or severe liver disease. It should also be avoided in those with hypersensitivity to ticagrelor or any of its components.

Reference 

1. Mayo Clinic. Ticagrelor (oral route) description and brand names [Internet]. Rochester (MN): Mayo Foundation for Medical Education and Research; 2023 [cited 2025 Nov 4]. Available from. 
2. Drugs.com. Ticagrelor: MedFacts consumer information [Internet]. [updated 2024 Dec 1; cited 2025 Nov 4]. Available from. 
3. Kazi DS. Ticagrelor [Internet]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan– [cited 2025 Nov 4]. Available from. 
4. National Center for Biotechnology Information. PubChem Compound Summary for CID 9881411, Ticagrelor [Internet]. Bethesda (MD): National Library of Medicine (US); [cited 2025 Nov 4]. Available from. 

Siva Krishna Adithya Bhumireddy

Siva Krishna Adithya Bhumireddy completed a Bachelor of Pharmacy from GIET School of Pharmacy, affiliated with Andhra University, and from his 3rd year of graduation, he was working as a freelance medical and publication writer. Having expertise in systematic reviews and clinical research. With his keen interest and skills in research and documentation practices, he also reviewed more than 150 manuscripts from international journals like Elsevier, Springer Nature, and Sage Journals, and all the manuscripts were indexed and appeared in PubMed, Scopus, and Web of Science databases, and he received honorary recognition letters and certificates from all of them. Siva Krishna Adithya also published a few systematic, narrative reviews and a few chapters of international expertise.