Doxofylline 400 mg

Category- Allopathy

Medicine Highlights

Uses 1. To treat asthma  
2. To treat chronic bronchitis  
3. To treat COPD (Chronic Obstructive Pulmonary Disease) 
4. To treat Bronchospasm  
Common Side Effects  1.Headache 
2. Nausea or vomiting 
3. Stomach upset 
4. Trouble sleeping (insomnia) 
5. Feeling restless or anxious 
6. Increased heart rate 
Additional Information 1. This is a prescription medicine. Take it exactly as prescribed by your doctor. 
2. Avoid smoking, as it can reduce the medicine’s effect. 
3. Inform your doctor if you have heart, liver, or kidney problems. 
Storage 1- The medicine should be stored at room temperature 
2- Keep away from sunlight and moisture 
3- Keep away from the reach of children 
How to Take This MedicineThis medicine is meant to be used in the nose only 

Doxofylline Uses 

Doxofylline is a bronchodilator. It is useful for relieving symptoms caused by narrowing of the airways, which makes breathing difficult in the following conditions: 

  1. Asthma  
  2. Chronic bronchitis  
  3. COPD (Chronic Obstructive Pulmonary Disease) 
  4. Bronchospasm   

Directions for use

  1. If you forget to take this medicine, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. 
  2. Take this medicine exactly as prescribed by your doctor, at the same time each day.  
  3. Do not stop taking this medicine without your doctor’s approval, even if you feel better.

Doxofylline side effects 

More Common  

  1. Headache 
  2. Nausea or vomiting 
  3. Stomach upset 
  4. Trouble sleeping (insomnia) 
  5. Feeling restless or anxious 
  6. Increased heart rate  

Less Common

  1. Severe chest pain 
  2. Allergic reaction (rash, swelling, difficulty breathing) 
  3. Severe dizziness or fainting 

How Doxofylline works 

Doxofylline works by relaxing the muscles around your airways and opening them up, making it easier for air to move in and out of your lungs. This helps you breathe better, reduces wheezing, and eases chest tightness caused by asthma, COPD, or bronchitis. 

Safety Measures and Warning 

Allergy/hypersensitivity

It can cause serious allergic reactions like rash, swelling, or trouble breathing. Always check with your doctor first. 

Heart problems

This medicine can make your heartbeat too fast or irregular doctor supervision is crucial. 

High blood pressure

It can raise your blood pressure even more consult your doctor before taking it. 

Epilepsy or seizures

It may make seizures more likely talk to your doctor to see if it’s safe.

Allergic individuals

If you are allergic to Oxymetazoline or any ingredients in the drops, using it can cause swelling, rash, or difficulty breathing. 

Liver or kidney problems

If you’re suffering with liver and kidney diseases your body cannot remove this medicine properly; it can stay in your system and may cause harmful side effects. Communicate with your doctor 

Children

Children need very small doses and taking too much can be unsafe get a doctor’s guidance before use. 

Doxofylline Interaction with Other Medicines

Avoid taking Doxofylline with the following medicines, as it may increase or decrease the desired effect, or in worse cases and it could be fatal: 

Doxofylline Interaction with Food Product

Avoid caffeine, alcohol, and smoking before or after taking the drug, as they can alter its effect and cause drowsiness or sedation. 

Storage

  1. Store the medicine at room temperature 
  2. Keep away from sunlight and moisture 
  3. Keep out of reach of children 

Doxofylline Chemical Structure

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione 

Intake routine/cycle

Daily dose

Take Doxofylline exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor. 

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage. 

Overdose

Doxofylline dosage should not exceed 1,200 mg/day. Symptoms for overdosing include dizziness or lightheadedness when getting up suddenly from a lying or sitting position. In case of an overdose or any severe symptoms, seek immediate medical attention.

Doxofylline Summary

Doxofylline is a medicine used to treat breathing problems like asthma, chronic bronchitis, bronchospasm and COPD. It works by relaxing the muscles around the airways by making space for the maximum air to pass into the lungs, by which breathing becomes easier and wheezing or chest tightness is reduced.  

Common side effects may include headache, nausea, stomach upset, trouble sleeping, restlessness, and a faster heartbeat. Rarely, it can cause serious reactions like severe chest pain, allergic reactions, or dizziness. Always take it as prescribed and follow your doctor’s advice. 

FAQ’s

What are the uses for doxofylline? 

Doxofylline is used to treat breathing problems like asthma, chronic bronchitis, and COPD. It helps open the airways and makes breathing easier. 

What are the common side effects of doxofylline? 

Common side effects of doxofylline include headache, nausea, stomach upset, trouble sleeping, restlessness, and faster heartbeat. 

What is the price of doxofylline 400mg tablets? 

Doxofylline 400mg price at SayaCare’s online pharmacies is about 24 rupees, at SayaCare we provide test report with each medicine. Also, at SayaCare we provide you with up to 80% less cost than the market. 

Reference 

  1. Doxofylline [Internet]. go.drugbank.com. Available from 
  2. 1mg.com. Doxofylline: View Uses, Side Effects and Medicines | 1mg [Internet]. 1mg. 2024 [cited 2025 Sep 24]. Available from 
  3. PubChem. Doxofylline [Internet]. Nih.gov. PubChem; 2024. Available from 
  4. Doxofylline – Uses, Dosage, Side Effects, Price, Composition | Practo [Internet]. www.practo.com. Available from 

Authors

  • Pranathi Chintaluri

    Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children's health” which will be published by the end of 2025.

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  • Mahak Phartyal

    Mahak Phartyal completed her bachelor's in pharmacy from Veer Madho Singh Bhandari Uttarakhand Technical University. She previously worked as a Medical Writer at Meril Life Sciences, where she wrote numerous scientific abstracts for conferences such as India Live 2024 and the European Society of Cardiology (ESC). During her college years, she developed a keen research interest and published an article titled “Preliminary Phytochemical Screening, Physicochemical and Fluorescence Analysis of Nyctanthes arbor-tristis and Syzygium cumini Leaves.

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