Clotrimazole 1% + Beclomethasone 0.025%

Category- Allopathy

Medicine Highlights

Clotrimazole + Beclomethasone Uses 

Clotrimazole 1% + Beclomethasone 0.025% is a topical lotion belonging to the class of antifungal and corticosteroid combination medicines. This lotion is helpful in treating fungal infection of the:  

1. Feet 
2. Groin area 
3. Skin causing redness, itching and swelling 

Directions for use

1. If you forget to take this medicine, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. 
2. Take this medicine exactly as prescribed by your doctor, at the same time each day.  
3. Do not stop taking this medicine without your doctor’s approval, even if you feel better.

Clotrimazole + Beclomethasone side effects 

More Common  

1. Burning or stinging sensation at the application site 
2. Itching or irritation on the skin 
3. Dryness or peeling of the skin 
4. Redness at the site of application 

Less Common

1. Skin thinning (atrophy) 
2. Stretch marks (striae) 
3. Acne or pimples on treated area 
4. Increased hair growth on application site 
5. Secondary skin infections 
6. Allergic reaction (rash, swelling, severe itching) other areas 
7. Allergic reactions

How Clotrimazole + Beclomethasone works 

Clotrimazole + beclomethasone works by combining the antifungal action of clotrimazole with the anti-inflammatory effect of beclomethasone. Clotrimazole kills or stops the growth of fungi by inhibiting the synthesis of ergosterol, an essential component of the fungal cell membrane. This weakens and damages the fungal cell, leading to its death. Beclomethasone, a corticosteroid, reduces inflammation by blocking the release of chemicals that cause redness, itching, and swelling. Together, this combination not only eliminates fungal infection but also provides quick relief from symptoms like itching, irritation, and redness, promoting faster healing and comfort. 

Safety Measures and Warning 

Allergy/Hypersensitivity

If you have an allergy to clotrimazole or other antifungal medicines, inform your doctor before use. 

Pregnancy

This combination should be used with caution during pregnancy and only if clearly prescribed by a doctor. Prolonged or excessive use of corticosteroid-containing creams during pregnancy may affect fetal growth. Always consult your doctor if you are pregnant or planning to conceive. 

Breastfeeding

Avoid applying it on the breast area during breastfeeding. Prolonged use over large areas should be avoided to prevent absorption into breast milk. 

Skin Infections (Non-fungal)

Do not use this cream on bacterial, viral (like herpes, chickenpox), or tubercular skin infections, as it may worsen the condition. 

Broken or Damaged Skin

Avoid applying it on open wounds, ulcers, or severely damaged skin because it can increase systemic absorption of steroids. 

Chronic Skin Conditions

People with chronic skin disorders (such as psoriasis) should use them under strict medical supervision as corticosteroids can cause complications if misused. 

Clotrimazole + Beclomethasone Interaction with Other Medicines

Avoid taking clotrimazole + beclomethasone with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal: 

Clotrimazole + Beclomethasone Interaction with Food Product

Avoid excessive alcohol consumption and smoking during treatment, as it can weaken your immune system and slow healing of skin infections also limit excessive intake of caffeine as it can increase stress hormones, which sometimes worsen skin conditions. 

Storage

1. Store the medicine at room temperature 
2. Keep away from sunlight and moisture 
3. Keep out of reach of children 

Clotrimazole + Beclomethasone Chemical Structure

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Clotrimazole: 1-[(2-chlorophenyl)-diphenylmethyl]imidazole 

Beclomethasone: 11β,16β)-9-chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 

Intake routine/cycle

Daily dose

Take clotrimazole + beclomethasone exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor. 

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage. 

Overdose

Apply clotrimazole + beclomethasone cream/lotion as per doctor’s instruction do not consume orally. Overdose symptoms may include skin thinning, irritation, stretch marks, and rarely hormonal imbalance. 

Clotrimazole + Beclomethasone Summary

Clotrimazole + Beclomethasone is a combination lotion used to treat fungal infections on the skin, especially when they cause redness, itching, swelling, or irritation. It is effective against fungal infections on the feet, groin area, and other parts of the skin. It contains two main ingredients: clotrimazole, which works by destroying the skin of the fungus and stopping its growth and beclomethasone, a steroid that reduces inflammation, swelling, redness, and severe itching, giving quick relief from discomfort.   

Common side effects include mild burning, stinging, dryness, or redness at the application site. Rarely, cream/ lotion is used for too long or on large areas, it may cause skin thinning, stretch marks and bruising. Always use this cream/lotion exactly as prescribed, apply a thin layer on the affected area after cleaning and drying it, and avoid using it on open wounds or near the eyes. Do not cover the area with tight bandages unless told by a doctor, and do not use it longer than advised because steroids can cause harm if overused. 

FAQ’s

What are the uses of Clotrimazole cream? 

Clotrimazole cream treats fungal infections on the skin, foot infections, and groin infections. It also reduces itching, redness, and irritation caused by these infections. 

What is the price of clotrimazole 1% powder? 

Clotrimazole 1% powder price at SayaCare is about 66 rupees, at SayaCare we provide test report with each medicine. Also, at SayaCare we provide you with up to 80% less cost than the market. 

What are the side effects of Clotrimazole cream? 

Common side effects include itching, burning, redness, or mild stinging at the application site. Less common side effects may include blistering, swelling, spreading rash, or rare allergic reactions. 

How does Clotrimazole work? 

Clotrimazole is an antifungal medicine that works by disrupting the skin of the fungi and ultimately killing them. By targeting the fungal cells, it helps clear infections on the skin, nails, or mucous membranes and relieves symptoms such as itching, redness, burning, and irritation. 

How does Betamethasone work? 

Betamethasone works by reducing swelling, redness, and itching on the skin. It does this by blocking chemicals in the body that cause inflammation and irritation. 

Can Beclomethasone be used during pregnancy? 

Beclomethasone should be used during pregnancy only if a doctor advises it. Using too much or for a long time may affect the baby’s growth, so always consult your doctor before applying this medicine when pregnant. 

What is the price of clotrimazole and beclomethasone cream price cream? 

Clotrimazole and beclomethasone cream price at SayaCare is about 30 rupees, at SayaCare we provide test report with each medicine. Also, at SayaCare we provide you with up to 80% less cost than the market. 

Reference 

1. PubChem. Clotrimazole [Internet]. pubchem.ncbi.nlm.nih.gov. Available from 
2. Drugbank. Clotrimazole [Internet]. Drugbank. 2005. Available from 
3. Clotrimazole: Antifungal Skin Cream [Internet]. Cleveland Clinic. Available from 
4. Khatter NJ, Khan MA. Clotrimazole [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2020. Available from 
5. Truemeds [Internet]. Truemeds.in. 2019 [cited 2025 Aug 21]. Available from 
6. PubChem. Beclomethasone [Internet]. pubchem.ncbi.nlm.nih.gov. 2021. Available from 

Pranathi Chintaluri

Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.