Telmisartan 40 mg + Hydrochlorothiazide 12.5 mg

Category- Allopathy

Medicine Highlights

Telmisartan + Hydrochlorothiazide Summary 

Telmisartan + Hydrochlorothiazide helps lower high blood pressure by relaxing blood vessels and removing excess water. Take it daily as prescribed, and don’t stop without your doctor’s advice.  

Common side effects include dizziness, nausea, and flu-like symptoms, while serious ones like muscle cramps or trouble breathing need medical attention. Avoid alcohol and certain medications without consulting your doctor. In case of overdose, watch for dizziness or confusion and seek immediate help. 

Telmisartan + Hydrochlorothiazide Uses 

Telmisartan + Hydrochlorothiazide is an oral medication that belongs to the class of angiotensin II receptor blockers and diuretics (which increase urine production). It is used to treat high blood pressure (hypertension). 

Directions for use 

1. Take telmisartan + hydrochlorothiazide exactly as prescribed by your doctor, regularly at the same time each day. 
2. Do not stop taking telmisartan + hydrochlorothiazide without your doctor’s approval, even if you feel better. 
3. If you forget to take the medicine, take it as soon as you remember, unless it’s almost time for the next one, then just skip it. 

Telmisartan + Hydrochlorothiazide side effects

More Common

1. Dizziness 
2. Sinusitis 
3. Diarrhea 
4. Tiredness 
5. Nausea 
6. Infection in the nose or throat, sore throat, or common cold symptoms 
7. Flu-like symptoms 

Less Common

1. Bladder pain 
2. Bloody or cloudy urine 
3. Blurred vision 
4. Confusion 
5. Decreased urine 
6. Difficult, burning, or painful urination 
7. Dizziness, faintness, or lightheadedness when getting up from a lying or sitting position 
8. Dry mouth 
9. Fainting 
10. Fast, pounding, or irregular heartbeat or pulse 
11. Frequent urge to urinate 
12. Increased thirst 
13. Loss of appetite 
14. Lower back or side pain 
15. Muscle pain or cramps 
16. Nausea or vomiting 
17. Numbness or tingling in the hands, feet, or lips 
18. Seizures 
19. Sudden sweating 
20. Trouble breathing 
21. Unusual tiredness or weakness 

How Telmisartan + Hydrochlorothiazide works 

Our body has receptors called angiotensin II receptors, where the hormone angiotensin binds, causing blood vessels to contract and increasing blood pressure. Telmisartan works by blocking this binding, helping to relax blood vessels. Hydrochlorothiazide then removes excess water from the body through urine. Together, they help lower blood pressure effectively. 

Safety Measures and warning

1- Kidney Disease

If you have a pre-existing kidney disease, inform your doctor, as this medicine increases urine production, which may put extra strain on your kidneys.

2- Electrolyte Deficiency

Since this medicine increases urine production, it can lead to the loss of essential ions. If you are already electrolyte-deficient, it may worsen your condition. Therefore, it is best to inform your doctor.

3- Allergy/Hypertension

f you have a known allergy to this medicine, inform your doctor before use.

Telmisartan + Hydrochlorothiazide Interaction with Other Medicines 

Avoid taking telmisartan + hydrochlorothiazide with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal: 

Telmisartan + Hydrochlorothiazide Interaction with Food Product

Telmisartan + hydrochlorothiazide does not interact with any food products, but alcohol should be avoided before and after taking the medicine, as it can increase or decrease the effect of the medicine. 

Storage

1. The medicine should be stored at room temperature  
2. Keep away from sunlight and moisture  
3. Keep away from the reach of children 

Telmisartan + Hydrochlorothiazide Chemical Structure 

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name– 

Telmisartan- 2-[4-[[4-methyl-6-(1-methylbenzoimidazol-2-yl)-2-propyl-benzoimidazol-1-yl]methyl]phenyl]benzoic acid. 

Hydrochlorothiazide- 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide. 

Intake routine/cycle

Daily Dose

Take telmisartan + hydrochlorothiazide exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

If someone you know who takes this medicine has symptoms like dehydration, dizziness and confusion then take them to hospital immediately.

FAQ’s

1- How long does Telmisartan take to work?

You will experience the full effect of Telmisartan in approximately 3 hours. 

2- What is the use of Telmisartan and Hydrochlorothiazide tablets?

Telmisartan + Hydrochlorothiazide is used to treat high blood pressure (hypertension).

3- How does Telmisartan work?

Our body has receptors called angiotensin II receptors, where the hormone angiotensin binds, causing blood vessels to contract and increasing blood pressure. Telmisartan works by blocking this binding, helping to relax blood vessels and reduce blood pressure.

Reference

1. Mayo Clinic. Telmisartan and Hydrochlorothiazide (Oral Route) – Description [Internet]. Rochester (MN): Mayo Foundation for Medical Education and Research; [cited 2025 Mar 26]. Available from. 
2. WebMD. Telmisartan-Hydrochlorothiazide Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing [Internet]. [cited 2025 Mar 26]. Available from. 
3. GoodRx. What is Telmisartan? [Internet]. [cited 2025 Mar 26]. Available from. 

Mahak Phartyal

Mahak Phartyal completed her bachelor’s in pharmacy from Veer Madho Singh Bhandari Uttarakhand Technical University. She previously worked as a Medical Writer at Meril Life Sciences, where she wrote numerous scientific abstracts for conferences such as India Live 2024 and the European Society of Cardiology (ESC). During her college years, she developed a keen research interest and published an article titled “Preliminary Phytochemical Screening, Physicochemical and Fluorescence Analysis of Nyctanthes arbor-tristis and Syzygium cumini Leaves.