Category- Allopathy
About Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg
Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg tablet is used to control blood sugar in people with type 2 diabetes. Glimepiride helps the pancreas release more insulin, Metformin (SR) reduces sugar made by the liver and improves how the body responds to insulin, and voglibose makes the body use insulin more effectively. Together, they keep blood sugar under control and lower the risk of diabetes complications. Common side effects include low blood sugar, nausea, stomach upset, diarrhea, bloating, weight gain, swelling, headache, and dizziness. It should always be taken with food, meals should not be skipped, and alcohol should be avoided. Taking more than 1000 mg of combination per day can be dangerous and may cause nausea, vomiting, headache, tremors, restlessness, and rapid heartbeat.
Medicine Highlights
| Uses | 1. To manage type 2 Diabetes mellitus. – To maintain adequate Blood sugar levels |
| Common Side Effects | 1. Low blood sugar (hypoglycemia) 2. Nausea 3. Stomach pain 4. Diarrhea 5. Vomiting 6. Headache 7. Dizziness 8. Weakness |
| Additional Information | 1. Avoid consuming alcohol and tobacco with this medicine 2. It is usually taken once daily, preferably in the evening, or as prescribed by your doctor. |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | Swallow this medicine with water. |
Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg Uses
Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg is used to treat Type 2 diabetes mellitus. This medicine belongs to antidiabetics category.
Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg side effects
More Common
- Low blood sugar (hypoglycemia)
- Nausea
- Stomach pain
- Diarrhea
- Vomiting
- Headache
- Dizziness
- Weakness
Less Common
- Skin rash
- Itching
- Loss of appetite
- Metallic taste in mouth
- Breathing difficulty
- Lactic acidosis
How Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mgworks
Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg tablet works by lowering blood sugar levels in different ways. Glimepiride increases insulin release from the pancreas, while Metformin reduces glucose production in the liver and improves insulin sensitivity. Together, they help control blood sugar effectively in people with type 2 diabetes.
Safety Measures and Warning
Pregnancy
Pregnant women should take Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg, take only if advised by a doctor, because blood sugar control during pregnancy needs careful monitoring
Breastfeeding
Breastfeeding mothers should consult a doctor before taking Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg, as it may pass into breast milk.
Kidney and Liver Problems
People with kidney disease should use Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg carefully and only under medical advice, as Metformin may accumulate and increase the risk of lactic acidosis.
Low Blood Sugar
Do not skip meals while taking Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg, as it may cause hypoglycemia leading to sweating, dizziness, confusion, or fainting.
Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg Interaction with Food Product
Take Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg, with food to reduce stomach upset and prevent low blood sugar. Avoid alcohol, as it may increase the risk of hypoglycemia and lactic acidosis. Maintain a healthy diabetic diet and regular exercise for better blood sugar control.
Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg Interaction with Other Medicines
Avoid taking Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg combination with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg Chemical Structure
IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name
Metformin- N, N-dimethylimidodicarbonimidic diamide
Glimepiride—3‑Ethyl‑4‑methyl‑N‑[2‑(4‑{[(trans‑4‑methylcyclohexyl) carbamoyl] sulfamoyl} phenyl)ethyl]‑2‑oxo‑2,5‑dihydro‑1H‑pyrrole‑1‑carboxamide
Voglibose- 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
Intake routine/cycle
Daily dose
Take Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor
Missed Dose
If you forget to take Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg, take the medication soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Overdose
It is not recommended to take more than the prescribed dose. Taking too much may cause nausea, vomiting, diarrhea, stomach pain, or severe abdominal discomfort. In rare cases, allergic reactions may occur. Seek immediate medical attention if any severe symptoms develop.
Storage
- Store the medicine at room temperature
- Keep away from sunlight and moisture
- Keep out of reach of children
Directions for use
- Take Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg exactly as prescribed by your doctor, at the same time each day.
- Do not stop taking Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg without your doctor’s approval, even if you feel better.
- If you forget to take Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose.
FAQ’s
What is the mode of action of Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg?
Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg works by lowering blood sugar levels in two ways. Glimepiride increases the release of insulin from the pancreas, while Metformin reduces glucose production in the liver and improves the body’s response to insulin. Together, they help control blood sugar in people with type 2 diabetes.
What are the uses of Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg?
Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg tablets are used to treat type 2 diabetes mellitus. They help control high blood sugar levels, improve insulin action, and reduce the risk of diabetes-related complications when combined with proper diet and exercise.
What are the side effects of Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg tablets?
Common side effects of Glimepiride 3 mg + Voglibose 0.3 mg + Metformin 500 mg tablets include low blood sugar, nausea, stomach pain, diarrhea, vomiting, headache, dizziness, and weakness. Some people may also experience loss of appetite or a metallic taste in the mouth.
Reference
- PubChem. Metformin hydrochloride [Internet]. pubchem.ncbi.nlm.nih.gov. Available from
- Glimepiride [Internet]. Drugs.com. c2026 [cited 2026 Jul 18]. Available from.
- Drugs.com. Voglibose [Internet]. Drugs.com International. [cited 2025 Aug 14]. Available from.
- DrugBank Online. Voglibose [Internet]. Edmonton (AB): DrugBank; [cited 2025 Aug 14]. Available from.
- Kumar V, Abbas AK, Aster JC. Robbins Basic Pathology. 10th ed. Philadelphia: Elsevier; 2017. Chapter 25, The Endocrine System [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); [cited 2025 Aug 14]. Available from.
Authors
Siva Krishna Adithya Bhumireddy completed a Bachelor of Pharmacy from GIET School of Pharmacy, affiliated with Andhra University, and from his 3rd year of graduation, he was working as a freelance medical and publication writer. Having expertise in systematic reviews and clinical research. With his keen interest and skills in research and documentation practices, he also reviewed more than 150 manuscripts from international journals like Elsevier, Springer Nature, and Sage Journals, and all the manuscripts were indexed and appeared in PubMed, Scopus, and Web of Science databases, and he received honorary recognition letters and certificates from all of them. Siva Krishna Adithya also published a few systematic, narrative reviews and a few chapters of international expertise.