Aluminum hydroxide 250mg + Magnesium hydroxide 250 mg + Activated dimethicone 50mg

Category- Allopathy

About Aluminum hydroxide 250mg + Magnesium hydroxide 250 mg + Activated dimethicone 50mg

This medicine contains Aluminum Hydroxide 250 mg + Magnesium Hydroxide 250 mg + Activated Dimethicone 50 mg and is used to relieve acidity, heartburn, indigestion, gas, bloating, and stomach discomfort caused by excess stomach acid. 

Aluminum hydroxide and magnesium hydroxide are antacids that work by neutralizing excess acid in the stomach. Activated dimethicone (simethicone) helps break down gas bubbles in the stomach and intestines, reducing bloating, fullness, and discomfort. 

Common side effects include constipation, diarrhea, nausea, stomach discomfort, and chalky taste. These effects are usually mild and temporary. This medicine should be used with caution in people with severe kidney disease and those taking other medications that may interact with antacids. This combination is commonly used to provide quick relief from acidity, indigestion, and gas-related discomfort.    

Medicine Highlights

Aluminum hydroxide 250mg + Magnesium hydroxide 250 mg + Activated dimethicone 50mg Uses

Aluminum hydroxide 250mg + Magnesium hydroxide 250 mg + Activated dimethicone 50mg is used to treat and relieve: 

1. Acidity and Heartburn 
2. Indigestion 
3. Gas and bloating 
4. Stomach discomfort                  

Aluminum hydroxide 250mg + Magnesium hydroxide 250 mg + Activated dimethicone 50mg side effects 

More Common

1. Constipation 
2. Diarrhea 
3. Nausea 
4. Stomach discomfort 
5. Chalky taste 
6. Bloating 
7. Belching 
8. Vomiting            

Less Common 

1. Headache 
2. Dizziness 
3. Muscle weakness 
4. Allergic reactions 
5. Low phosphate levels with long-term use         

How Aluminum hydroxide 250mg + Magnesium hydroxide 250 mg + Activated dimethicone 50mg works 

This medicine contains aluminum hydroxide, magnesium hydroxide, and activated dimethicone works by reducing symptoms caused by excess stomach acid and gas. Aluminum hydroxide and magnesium hydroxide neutralize excess acid in the stomach, providing relief from acidity, heartburn, and indigestion. Activated dimethicone helps break up gas bubbles in the stomach and intestines, making it easier for gas to pass and reduce bloating, fullness, and discomfort. 

Safety Measures and Warning 

Allergy/Hypersentivity

If you are allergic to this medicine, this can cause serious allergic reactions such as skin rash, itching, swelling of the face or throat, breathing difficulty, or severe reactions. Hence, inform your doctor if you have any history of allergy to painkillers before taking this medicine.

Kidney Disease

If you have kidney problems, this medicine may worsen kidney function and reduce urine output. Hence, inform your doctor so the dose can be adjusted or avoided if necessary.

Liver Disease

If you have liver disease, this medicine may affect liver function and cause complications. Hence, inform your doctor before taking it.

Aluminum hydroxide 250mg + Magnesium hydroxide 250 mg + Activated dimethicone 50mg Interaction with Food Product 

Take this medicine after food to reduce stomach irritation and prevent discomfort. Taking it on an empty stomach may cause nausea or acidity. Alcohol should be avoided, as it can increase the risk of stomach irritation and bleeding.  

Aluminum hydroxide 250mg + Magnesium hydroxide 250 mg + Activated dimethicone 50mg Interaction with Other Medicines  

Avoid taking Aluminum hydroxide 250mg + Magnesium hydroxide 250 mg + Activated dimethicone 50mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

Aluminum hydroxide 250mg + Magnesium hydroxide 250 mg + Activated dimethicone 50mg Chemical Structure

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Magnesium hydroxide: Magnesium dihydroxide 

Dimethicone: poly(dimethylsiloxane) 

Aluminum hydroxide: aluminum trihydroxide

Intake routine/cycle

Daily dose

Take Aluminum hydroxide 250mg + Magnesium hydroxide 250 mg + Activated dimethicone 50mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

It is not recommended to take more than the prescribed dose of this suspension, as overdose may cause severe diarrhea, constipation, electrolyte imbalance, confusion, muscle weakness, or abnormal magnesium levels. Seek immediate medical attention if overdose symptoms occur.

Storage

1. Store the medicine at room temperature. 
2. Keep away from sunlight and moisture. 
3. Keep out of reach of children 

Directions for use 

1. Take Aluminum hydroxide 250mg + Magnesium hydroxide 250 mg + Activated dimethicone 50mg exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking Aluminum hydroxide 250mg + Magnesium hydroxide 250 mg + Activated dimethicone 50mg without your doctor’s approval, even if you feel better. 
3. If you forget to take Aluminum hydroxide 250mg + Magnesium hydroxide 250 mg + Activated dimethicone 50mg, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. 

FAQ’s

What are the side effects of magnesium hydroxide? 

Common side effects include diarrhea, stomach cramps, nausea, and watery stools. Rarely, it may cause electrolyte imbalance, weakness, or slow heartbeat, especially with overuse or in people with kidney problems. 

Can magnesium hydroxide be used for constipation? 

Yes, magnesium hydroxide is commonly used to relieve occasional constipation by drawing water into the intestines, which softens the stool and promotes bowel movement within 6 to 12 hours. 

What is magnesium hydroxide also known as? 

Magnesium hydroxide is also known as magnesium hydroxide, which is its active ingredient. 

Is magnesium hydroxide safe during pregnancy? 

Magnesium hydroxide is generally considered safe during pregnancy when used occasionally and at the recommended dose. However, it should be used under a doctor’s advice 

What are the uses of Aluminum Hydroxide? 

Aluminum Hydroxide is used to treat acidity, heartburn, acid indigestion, acid reflux, and stomach discomfort caused by excess stomach acid. It may also be used to lower high phosphate levels in people with kidney disease. 

What are the side effects of Aluminum Hydroxide? 

Common side effects include constipation, nausea, stomach discomfort, vomiting, and a chalky taste in the mouth. Rarely, it may cause allergic reactions or low phosphate levels with long-term use. 

Reference  

1. PubChem. Dimethicone [Internet]. pubchem.ncbi.nlm.nih.gov. Available from 
2. Lewsley J. What is dimethicone? Uses, safety, and alternatives [Internet]. 2022. Available from 
3. PubChem. Magnesium Hydroxide [Internet]. @pubchem. PubChem; 2023. Available from 
4. Drugbank. Magnesium hydroxide [Internet]. go.drugbank.com. 2015. Available from 
5. Phillips Milk Of Magnesia Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing – WebMD [Internet]. Webmd.com. 2025 [cited 2025 Jul 25]. Available from 
6. PubChem. Aluminum Hydroxide [Internet]. Nih.gov. PubChem; 2026. Available from 
7. Shon NN, Yarbrough T, Shah AD. Aluminum Hydroxide [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2020. Available from         

Pranathi Chintaluri

Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.