Category- Allopathy
About Magaldrate, Simethicone and Oxetacaine oral suspension
Magaldrate, Simethicone and Oxetacaine oral suspension are used to relieve acidity, heartburn, indigestion, gastritis, stomach discomfort, bloating, and pain associated with excess stomach acid. This medicine consists of active ingredients such as magaldrate, simethicone, and oxetacaine, where magaldrate works by neutralizing excess stomach acid, simethicone helps break down gas bubbles and relieves bloating, and oxetacaine acts as a local anesthetic that provides relief from stomach pain and burning sensations.
Common side effects include constipation, diarrhea, nausea, chalky taste, dry mouth, and stomach discomfort. In rare cases, it may cause allergic reactions, low phosphate levels, or severe gastrointestinal disturbances that require immediate medical attention.
Taking more than the recommended dose may cause severe constipation, diarrhea, stomach discomfort, nausea, vomiting, weakness, or electrolyte imbalance. Seek immediate medical attention if overdose symptoms occur.
Medicine Highlights
| Uses | 1. To treat acidity and heartburn 2. To relieve indigestion 3. To manage gastritis 4. To relieve bloating and excess gas 5. To reduce stomach pain and burning sensation |
| Common Side Effects | 1. Constipation 2. Diarrhea 3. Nausea 4. Dry mouth 5. Chalky taste 6. Stomach discomfort |
| Additional Information | To keep you safe and healthy, use this medicine only with your doctor’s guidance. |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | Take this medication orally using a measuring cup, spoon, or dropper as prescribed by your doctor. |
Magaldrate, Simethicone and Oxetacaine oral suspension Uses
Magaldrate, Simethicone and Oxetacaine oral suspension is used to treat the following conditions:
- Acidity and Heartburn
- Gastritis
- Indigestion
- Acid reflux and Bloating
- Stomach pain associated with excess acid
Magaldrate, Simethicone and Oxetacaine oral suspension side effects
More Common
- Constipation
- Diarrhea
- Nausea
- Dry mouth
- Chalky taste
- Stomach discomfort
Less Common
- Allergic reactions
- Vomiting
- Electrolyte imbalance
- Low phosphate levels
- Weakness
- Skin rash
How Magaldrate, Simethicone and Oxetacaine oral suspension works
This medicine consists of active ingredients such as magaldrate 540 mg, simethicone 50 mg, and oxetacaine 10 mg that work together to provide relief from acidity and stomach discomfort. Magaldrate neutralizes excess stomach acid and reduces irritation of the stomach lining. Simethicone helps break down gas bubbles in the stomach and intestines, reducing bloating and discomfort. Oxetacaine is a local anesthetic that relieves pain and burning sensations in the stomach and food pipe. Together, they provide effective relief from acidity, heartburn, gas, and stomach pain.
Safety Measures and Warning
Allergy/Hypersentivity
If you are allergic to magaldrate, simethicone, oxetacaine, avoid using this medicine. Serious allergic reactions such as rash, itching, swelling, or breathing difficulty may occur.
Kidney Disease
If you have kidney disease, this medication should be avoided as this medicine contains magnesium and aluminum which might accumulate in the body and worsen your kidney disease. Always communicate with your doctor about your past disease history.
Gastrointestinal Disorders
Consult your doctor if you have persistent stomach pain, gastrointestinal bleeding, or difficulty swallowing.
Pregnancy and Breastfeeding
Use during pregnancy or breastfeeding only if recommended by your doctor.
Magaldrate, Simethicone and Oxetacaine oral suspension Interaction with Food Product
This oral suspension can be taken before meals or as advised by your doctor. Avoid excessive alcohol consumption, as it may worsen acidity and stomach irritation
Magaldrate, Simethicone and Oxetacaine oral suspension Interaction with Other Medicines
Avoid taking Magaldrate, Simethicone and Oxetacaine oral suspension with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Magaldrate, Simethicone and Oxetacaine oral suspension Chemical Structure
IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name
Magaldrate: pentaaluminum;decamagnesium;hentriacontahydroxide;disulfate;hydrate
Simethicone: dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane
Oxetacaine: 2-[2-hydroxyethyl-[2-[methyl-(2-methyl-1-phenylpropan-2-yl)amino]-2-oxoethyl]amino]-N-methyl-N-(2-methyl-1-phenylpropan-2-yl)acetamide
Intake routine/cycle
Daily dose
Take Magaldrate, Simethicone and Oxetacaine oral suspension exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
Missed Dose
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Overdose
It is not recommended to take more than the prescribed dose of Magaldrate 540 mg + Simethicone 50 mg + Oxetacaine 10 mg/5 ml oral suspension. Overdose may cause severe constipation, diarrhea, nausea, vomiting, stomach discomfort, weakness, electrolyte imbalance, or low phosphate levels. Seek immediate medical attention if overdose symptoms occur.
Storage
- Store the medicine at room temperature.
- Keep away from sunlight and moisture.
- Keep out of reach of children
Directions for use
- Take Magaldrate, Simethicone and Oxetacaine oral suspension exactly as prescribed by your doctor, at the same time each day.
- Do not stop taking Magaldrate, Simethicone and Oxetacaine oral suspension without your doctor’s approval, even if you feel better.
- If you forget to take Magaldrate, Simethicone and Oxetacaine oral suspension, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose.
FAQ’s
What are the uses of Magaldrate, Simethicone and Oxetacaine oral suspension?
Magaldrate, Simethicone and Oxetacaine oral suspension is used to relieve acidity, heartburn, indigestion, gastritis, acid reflux, bloating, excess gas, and stomach pain caused by excess stomach acid.
How does Magaldrate, Simethicone and Oxetacaine oral suspension work?
Magaldrate neutralizes excess stomach acid, Simethicone breaks down gas bubbles to relieve bloating, and Oxetacaine acts as a local anesthetic to reduce stomach pain and burning sensations.
What are the common side effects of Magaldrate, Simethicone and Oxetacaine oral suspension?
Common side effects include constipation, diarrhea, nausea, dry mouth, chalky taste, and stomach discomfort. These side effects are usually mild and temporary.
How should Magaldrate, Simethicone and Oxetacaine oral suspension be taken?
Take the suspension exactly as prescribed by your doctor. Shake the bottle well before use and measure the dose using a measuring cup or spoon. It is usually taken before meals or as directed by your healthcare provider.
Who should avoid taking Magaldrate, Simethicone and Oxetacaine oral suspension?
People who are allergic to magaldrate, simethicone, oxetacaine, or any of the ingredients should avoid this medicine. Patients with severe kidney disease should use it only under medical supervision.
Reference
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- Magaldrate Uses, Side Effects & Warnings [Internet]. Drugs.com. 2026 [cited 2026 Jun 22]. Available from
- Mayo Clinic. Simethicone (Oral Route) Description and Brand Names – Mayo Clinic [Internet]. Mayoclinic.org. 2019. Available from
- Ingold CJ, Akhondi H. Simethicone [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2023. Available from
- Oxethazaine: Uses, Interactions, Mechanism of Action | DrugBank [Internet]. Drugbank.com. DrugBank; 2026 [cited 2026 Jun 22]. Available from
Authors
Pranathi is a final year Pharm D student at Chalapathi Institute of Pharmaceutical Sciences. She loves learning and applying her knowledge in pharmacy and has a passion for writing, which allows her to express ideas clearly and creatively. She enjoys combining her technical skills with her love for writing and communication to make a meaningful impact. Currently she is working on a research paper about “Consanguineous marriages and its impact on children’s health” which will be published by the end of 2025.